Evidence map›Paper›PMID 25079883›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2014

Pediatric spinal ependymomas: an unpredictable and puzzling disease. Long-term follow-up of a single consecutive institutional series of ten patients.

Tryggve Lundar, Bernt Johan Due-Tønnessen, David Scheie, Petter Brandal

Abstract read
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Current management in the treatment of intramedullary ependymomas in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
  4. Article
  5. Pediatric Spinal Ependymomas.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  6. Treatment patterns of children with spine and spinal cord tumors: national outcomes and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
    Review
  7. Article
  8. Article
  9. Posterior fossa ependymoma in childhood: 60 years event-free survival after partial resection—a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015
    Article
  10. Radiation therapy after subtotal resection of pediatric grade II/III spinal ependymomas: what is the evidence?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tryggve LundarDepartment of Neurosurgery, Oslo University Hospital, Postboks 4950, Nydalen, 0424, Oslo, Norway, tryggve.lundar@ous-hf.no.
Bernt Johan Due-Tønnessen
David Scheie
Petter Brandal

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsTen consecutive children (0-18 years) who underwent primary tumor resection for a spinal ependymoma between 1980 and 2011 were included in this retrospective study. Gross motor function and activities of daily life were scored according to the Barthel Index.

conclusionThree out of six pediatric patients treated for spinal myxopapillary ependymoma are disease-free after 11 to 33 years of follow-up. The other three have progressive disease, after relapses occurring after 4.5, 7, and 20 years, respectively. One out of two patients with grade II ependymoma had progressive disease from 10 years after initial surgery but is in full-time work in spite of widespread metastatic disease after 32 years. One of the two children with grade III tumor died from progressive disease 17 years from primary diagnosis, while the last one is tumor-free after 19 years. The quality of life is good for three of the four patients with widespread disease, and they are managed conservatively aiming at symptomatic treatment intervention if necessary. We strongly advocate lifelong follow-up for children treated for spinal ependymomas.

Indexed as

Activities of Daily LivingAdolescentAdultChildChild, PreschoolCohort StudiesDisease-Free SurvivalDisease ProgressionEpendymomaFemaleFollow-Up StudiesHumansInfantMaleNeurologic ExaminationRetrospective Studies

Identifiers

PMID25079883
PMCPMC4223574

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.