Evidence map›Paper›PMID 25079786›Full record

ArticleBMC medical genomics2014

Differentially private distributed logistic regression using private and public data.

Zhanglong Ji, Xiaoqian Jiang, Shuang Wang, Li Xiong, Lucila Ohno-Machado

Abstract read
In one paragraph

Article in BMC medical genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Privacy protection of medical data in social network.BMC medical informatics and decision making · 2021
    Article
  5. Article
  6. Protecting patient privacy in survival analyses.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  7. Article
  8. Privacy Policy and Technology in Biomedical Data Science.Annual review of biomedical data science · 2018
    Article
  9. Article
  10. Article
  11. Secure Multi-pArty Computation Grid LOgistic REgression (SMAC-GLORE).BMC medical informatics and decision making · 2016
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhanglong Ji
Xiaoqian Jiang
Shuang Wang
Li Xiong
Lucila Ohno-Machado

Funding

iDASH: Integrating Data for Analysis, Anonymization, and SharingU54HL108460 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OHNO-MACHADO, LUCILA · 2010 to 2015
$19.1M
SCANNER: Scalable National Network for Effectiveness ResearchR01HS019913 · AHRQ · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OHNO-MACHADO, LUCILA · 2010 to 2010
$8.3M
Protection of Records: Privacy (PReP) Technology for Medical ResearchR00LM011392 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JIANG, XIAOQIAN · 2013 to 2015
$650k
AHRQ HHS R01HS019913NCATS NIH HHS UL1TR0001000NHLBI NIH HHS U54HL108460NLM NIH HHS R00LM011392
6 · The paper itself

Abstract

backgroundPrivacy protecting is an important issue in medical informatics and differential privacy is a state-of-the-art framework for data privacy research. Differential privacy offers provable privacy against attackers who have auxiliary information, and can be applied to data mining models (for example, logistic regression). However, differentially private methods sometimes introduce too much noise and make outputs less useful. Given available public data in medical research (e.g. from patients who sign open-consent agreements), we can design algorithms that use both public and private data sets to decrease the amount of noise that is introduced. METHODOLOGY: In this paper, we modify the update step in Newton-Raphson method to propose a differentially private distributed logistic regression model based on both public and private data. EXPERIMENTS AND

resultsWe try our algorithm on three different data sets, and show its advantage over: (1) a logistic regression model based solely on public data, and (2) a differentially private distributed logistic regression model based on private data under various scenarios.

conclusionLogistic regression models built with our new algorithm based on both private and public datasets demonstrate better utility than models that trained on private or public datasets alone without sacrificing the rigorous privacy guarantee.

Indexed as

PrivacyAccess to InformationAlgorithmsBreast NeoplasmsData MiningHumansLogistic ModelsMedical InformaticsPatient Discharge

Identifiers

PMID25079786
PMCPMC4101668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.