ArticleChest2015
Factors predictive of airflow obstruction among veterans with presumed empirical diagnosis and treatment of COPD.
Article in Chest, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Elucidating the Relationship Between Body Fat Index and Pulmonary Health: Insights from Cross-Sectional Analysis and Mendelian Randomization.International journal of chronic obstructive pulmonary disease · 2025Article
- The Effect of Rurality and Poverty on COPD Outcomes in New Hampshire: An Analysis of Statewide Hospital Discharge Data.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2022Article
- Inhaled Medication Use in Smokers With Normal Spirometry.Respiratory care · 2021Article
- Overuse and Misuse of Inhaled Corticosteroids Among Veterans with COPD: a Cross-sectional Study Evaluating Targets for De-implementation.Journal of general internal medicine · 2020Article
- Accuracy of electronic health record data for the diagnosis of chronic obstructive pulmonary disease in persons living with HIV and uninfected persons.Pharmacoepidemiology and drug safety · 2019Article
- Inaccurate diagnosis of COPD: the Welsh National COPD Audit.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Article
- Observational
- Diagnosing Chronic Obstructive Pulmonary Disease Among Afghanistan and Iraq Veterans: Veterans Affair's Concordance With Clinical Guidelines for Spirometry Administration.Military medicine · 2017Article
- Outcomes of patients with chronic obstructive pulmonary disease diagnosed with or without pulmonary function testing.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017Article
- Prevalence of airflow obstruction in patients with stable systolic heart failure.BMC pulmonary medicine · 2017Article
- Overdiagnosis of COPD in hospitalized patients.International journal of chronic obstructive pulmonary disease · 2017Article
- Veterans Airflow Obstruction Screening Questionnaire: A Survey to Identify Veterans with Airflow Obstruction.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2016Article
- A case-control study of airways obstruction among construction workers.American journal of industrial medicine · 2015Article
- Implications of the GOLD COPD Classification and Guidelines.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2015Article
- Comorbidities and Chronic Obstructive Pulmonary Disease: Prevalence, Influence on Outcomes, and Management.Seminars in respiratory and critical care medicine · 2015Review
- Factors associated with inadequate diagnosis of COPD: On-Sint cohort analysis.International journal of chronic obstructive pulmonary disease · 2015Observational
- Undiagnosed and Misdiagnosed Chronic Obstructive Pulmonary Disease: Data from the BOLD Australia Study.International journal of chronic obstructive pulmonary diseaseArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDespite guideline recommendations, patients suspected of having COPD often are treated empirically instead of undergoing spirometry to confirm airflow obstruction (AFO). Accurate diagnosis and treatment are essential to provide high-quality, value-oriented care. We sought to identify predictors associated with AFO among patients with and treated for COPD prior to performance of confirmatory spirometry.
methodsWe identified a cohort of veterans with spirometry performed at Pacific Northwest Department of Veterans Affairs medical centers between 2003 and 2007. We included only patients with empirically diagnosed COPD in the 2 years prior to spirometry who were also taking inhaled medication to treat COPD in the 1 year prior to spirometry. We used relative risk regression analysis to identify predictors of AFO.
resultsAmong patients empirically treated for COPD (N = 3,209), 62% had AFO. Risk factors such as older age, prior smoking status, and underweight status were associated with AFO on spirometry. In contrast, comorbidities often associated with somatic symptoms were associated with absence of AFO and included congestive heart failure, depression, diabetes, obesity, and sleep apnea.
conclusionsComorbidities associated with somatic complaints of dyspnea were associated with a lower risk of having airflow limitations, suggesting that empirical diagnosis and treatment of COPD may lead to inappropriate treatment of individuals who do not have AFO.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.