Evidence map›Paper›PMID 25079592›Full record

Trial reportJournal of clinical pharmacology2015

Rilonacept pharmacokinetics in children with systemic juvenile idiopathic arthritis.

Julie Autmizguine, Michael Cohen-Wolkowiez, Norman Ilowite, RAPPORT Investigators

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Interleukin-1 Antagonists for the Treatment of Recurrent Pericarditis.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2022
    Review
  8. Review
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Julie AutmizguineDuke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA.
Michael Cohen-Wolkowiez
Norman Ilowite
RAPPORT Investigators
Clinical Research Institute · USAlbert Einstein College of Medicine · US

Funding

Duke CTSA (Composite)UL1TR001117 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, LI, JENNIFER S · 2013 to 2017
$41.3M
Clinical Practice Data to Aid Narrow Therapeutic Index Drug ClassificationU01FD004858 · FDA · DUKE UNIVERSITY · PI COHEN-WOLKOWIEZ, MICHAEL · 2013 to 2014
$497k
Pharmacokinetics and Pharmacodynamics of Antibiotics in Premature InfantsK23HD064814 · NICHD · DUKE UNIVERSITY · PI COHEN-WOLKOWIEZ, MICHAEL · 2010 to 2013
$474k
FDA HHS 1U01FD004858-01FDA HHS U01 FD004858NCATS NIH HHS UL1 TR001117NCATS NIH HHS UL1TR001117NIAMS NIH HHS HHSN268200700015CNIAMS NIH HHS N01 AR700015NICHD NIH HHS 1K23HD064814NICHD NIH HHS K23 HD064814
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Models, BiologicalAdolescentArthritis, JuvenileChildChild, PreschoolDouble-Blind MethodFemaleHumansInfantMaleRecombinant Fusion ProteinsSerum AlbuminRecombinant Fusion ProteinsrilonaceptSerum Albumininterleukin-1 inhibitorpediatricspopulation pharmacokineticssystemic juvenile idiopathic arthritis

Identifiers

PMID25079592
PMCPMC4276471
OpenAlexW1582179500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.