ArticleCritical care (London, England)2014
Early prediction of new-onset physical disability after intensive care unit stay: a preliminary instrument.
Article in Critical care (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prognostication of Need for Rehabilitation and Special Support in ICU Survivors. Two Studies Prognosticating Adverse Physical or Psychological Outcome
Web-based Follow-up to Former ICU Patients
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prediction Models for Physical, Cognitive, and Mental Health Impairments After Critical Illness: A Systematic Review and Critical Appraisal.Critical care medicine · 2020Pooled it
- Enhancing depression risk assessment in critical care nurses: a call for quantitative modeling.Critical care (London, England) · 2025Article
- Post-Intensive Care Syndrome: Physical Impairments and Function.Critical care clinics · 2025Review
- Risk prediction models for post-intensive care syndrome of ICU discharged patients: A systematic review.International journal of nursing sciences · 2025Review
- Development and validation of a machine learning-based model for post-sepsis frailty.ERJ open research · 2024Article
- Potential risk factors for reduced quality of life and increased health care utilization in ARDS survivors: results from the multicenter cohort study DACAPO.Critical care (London, England) · 2024Article
- Development and validation of early prediction models for new-onset functional impairment in patients after being transferred from the ICU.Scientific reports · 2024Article
- Latent Trajectories of Activities of Daily Living Disability and Associated Factors Among Adults with Post-Intensive Care Syndrome One Week After ICU Discharge.Journal of multidisciplinary healthcare · 2024Article
- Activity of Daily Living and Walking Ability of Patients with Severe COVID-19 at Discharge from an Acute Care Hospital.Progress in rehabilitation medicine · 2024Article
- Predictors of Activities of Daily Living in Intensive Care Unit Survivors: A Propensity Score Matching Analysis.Progress in rehabilitation medicine · 2023Article
- Long-term Survival after Critical Illness: Are We There Yet?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
- A Modified Physical Disability Screening Model after Treatment in the Intensive Care Unit: A Nationwide Derivation-Validation Study.Journal of clinical medicine · 2022Article
- Development and validation of early prediction models for new-onset functional impairment at hospital discharge of ICU admission.Intensive care medicine · 2022Article
- Acute kidney injury contributes to worse physical and quality of life outcomes in survivors of critical illness.BMC nephrology · 2022Article
- Article
- Incidence and risk factors for postintensive care syndrome in a cohort of critically ill patients.Revista Brasileira de terapia intensiva · 2022Observational
- Lean mass as a risk factor for intensive care unit admission: an observational study.Critical care (London, England) · 2021Observational
- National Trends and Variation of Functional Status Deterioration in the Medically Critically Ill.Critical care medicine · 2020Article
- Post-Intensive-Care Syndrome for the Pediatric Neurologist.Pediatric neurology · 2020Review
- Development of an ICU discharge instrument predicting psychological morbidity: a multinational study.Intensive care medicine · 2018Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMany intensive care unit (ICU) survivors suffer from physical disability for months after ICU stay. There is no structured method to identify patients at risk for such problems. The purpose of the study was to develop a method for early in-ICU prediction of the patient's individual risk for new-onset physical disability two months after ICU stay.
methodsIn total, 23 potential predictors for physical disability were assessed before individual ICU discharge. Two months after ICU discharge, out of 232 eligible patients, 148 ICU survivors (64%) completed the activity of daily living (ADL) staircase questionnaire to determine new-onset physical disability.
resultsA total of 95% percent of patients had no ADL reduction prior to ICU admission. 47% (n = 69) of questionnaire responders suffered from worsened ADL. We identified four independent predictors for new-onset physical disability: Low educational level (odds ratio (OR) =6.8), impaired core stability (OR = 4.6), fractures (OR = 4.5) and ICU length of stay longer than 2 days (OR = 2.6). The predictors were included in a screening instrument. The regression coefficient of each predictor was transformed into a risk score. The sum of risk scores was related to a predicted probability for physical disability in the individual patient. The cross-validated area under receiver operating characteristics curve (AUC) for the screening instrument was 0.80.
conclusionsEducational level is the single most important predictor for new-onset physical disability 2 months after ICU stay, followed by impaired core stability at ICU discharge, the presence of fractures and ICU stay longer than 2 days. A simple screening instrument based on these predictors can be used at ICU discharge to determine the risk for new-onset physical disability. This preliminary instrument may help clinicians to identify patients in need of support, but needs external validation prior to wider clinical use.
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