Evidence map›Paper›PMID 25078088›Full record

ArticlePLoS neglected tropical diseases2014

Patterns and risks of trichinella infection in humans and pigs in northern Laos.

James V Conlan, Khamphouth Vongxay, Boualam Khamlome, Maria Angeles Gomez-Morales, Edoardo Pozio, Stuart D Blacksell, Stanley Fenwick, R C A Thompson

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Review
  3. Observational
  4. Occurrence ofParasitology · 2024
    Article
  5. Review
  6. Exposure toPathogens (Basel, Switzerland) · 2024
    Article
  7. The Prevalence ofAnimals : an open access journal from MDPI · 2022
    Article
  8. Human trichinellosis in Southeast Asia, 2001-2021.Food and waterborne parasitology · 2022
    Article
  9. Article
  10. Seroprevalence and Associated Risk Factors of Trichinellosis andTropical medicine and infectious disease · 2022
    Article
  11. Review
  12. Low Prevalence of Cysticercosis andTropical medicine and infectious disease · 2021
    Article
  13. Article
  14. Article
  15. Seroprevalence ofBioMed research international · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Patterns of Flavivirus Seroprevalence in the Human Population of Northern Laos.The American journal of tropical medicine and hygiene · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 5 countries.

James V ConlanSchool of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia, Australia.
Khamphouth VongxayDivision of Veterinary Services, Department of Livestock and Fisheries, Ministry of Agriculture and Forestry, Vientiane, Laos.
Boualam KhamlomeDepartment of Communicable Diseases Control, Ministry of Health, Vientiane, Laos.
Maria Angeles Gomez-MoralesDepartment of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy.
Edoardo PozioDepartment of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy.
Stuart D BlacksellSchool of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia, Australia; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Churchill Hospital, Oxford, United Kingdom.
Stanley FenwickSchool of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia, Australia.
R C A ThompsonSchool of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia, Australia.
Murdoch University · AUIstituto Superiore di Sanità · ITMahidol University · THMinistry of Agriculture and Forestry · LAMinistry of Health · LA

Funding

Wellcome Trust
6 · The paper itself

Abstract

Several outbreaks of trichinellosis associated with the consumption of raw pork have occurred in Laos since 2004. This cross-sectional study was conducted in four provinces of northern Laos to investigate the seroepidemiology of trichinellosis in the human population and determine the prevalence and species of Trichinella infection in the domestic pig population. Serum samples and questionnaire data were obtained from 1419 individuals. Serum samples were tested for Trichinella antibodies by ELISA using larval excretory-secretory (ES) antigens and a subset of 68 positive samples were tested by western blot. The seroprevalence of Trichinella antibodies was 19.1% (95% confidence interval (CI) = 17.1-21.1%). The risk of having antibodies detected by ELISA using ES antigens increased with age, being of Lao-Tai ethnicity, living in Oudomxay province and being male. Tongue and diaphragm muscle samples were collected from 728 pigs and tested for Trichinella larvae by the artificial digestion method. Trichinella larvae were isolated from 15 pigs (2.1%) of which 13 were identified as T. spiralis by molecular typing; the species of the two remaining isolates could not be determined due to DNA degradation. Trichinella spp. are endemic in the domestic environment of northern Laos and targeted preventative health measures should be initiated to reduce the risk of further outbreaks occurring.

Indexed as

AdolescentAdultAgedAged, 80 and overAnimalsAntibodies, HelminthBlotting, WesternChildCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleHumansLaosMaleMiddle AgedRisk FactorsAntibodies, Helminth

Identifiers

PMID25078088
PMCPMC4117436
OpenAlexW1995098726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.