ArticleEuropean journal of nuclear medicine and molecular imaging2014
Intraoperative 3-D imaging improves sentinel lymph node biopsy in oral cancer.
Article in European journal of nuclear medicine and molecular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Diagnostic value of sentinel lymph node biopsy for cT1/T2N0 tongue squamous cell carcinoma: a meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017Pooled it
- Diagnostic Efficacy of Sentinel Lymph Node Biopsy in Early Oral Squamous Cell Carcinoma: A Meta-Analysis of 66 Studies.PloS one · 2017Pooled it
- iROLL: does 3-D radioguided occult lesion localization improve surgical management in early-stage breast cancer?European journal of nuclear medicine and molecular imaging · 2015Trial
- Feasibility and Performance of Free-Hand Single-Photon Computed Tomography/Ultrasonography for Preoperative Parathyroid Adenoma Localization: A Pilot Study.Diagnostics (Basel, Switzerland) · 2023Article
- Role of sentinel lymph node biopsy for oral squamous cell carcinoma: Current evidence and future challenges.Head & neck · 2023Review
- Evaluation of camera-based freehand SPECT in preoperative sentinel lymph node mapping for melanoma patients.EJNMMI research · 2020Article
- Sentinel ode apping in on-small ell ung ancer sing an ntraoperative adiotracer echnique.Asia Oceania journal of nuclear medicine & biology · 2019Article
- Intraoperative biophotonic imaging systems for image-guided interventions.Nanophotonics (Berlin, Germany) · 2019Article
- Merkel Cell Carcinoma of the Head and Neck: Recommendations for Diagnostics and Treatment.Annals of surgical oncology · 2017Review
- Introducing navigation during melanoma-related sentinel lymph node procedures in the head-and-neck region.EJNMMI research · 2017Article
- Sentinel Lymph Node Biopsy: A new approach in the management of head and neck cancers.Sultan Qaboos University medical journal · 2017Review
- Fusion of freehand SPECT and ultrasound: First experience in preoperative localization of sentinel lymph nodes.European journal of nuclear medicine and molecular imaging · 2016Article
- Hybrid surgical guidance based on the integration of radionuclear and optical technologies.The British journal of radiology · 2016Review
- Fusion of Freehand SPECT and Ultrasound to Perform Ultrasound-Guided Fine-Needle Aspiration Cytology of Sentinel Nodes in Head and Neck Cancer.AJNR. American journal of neuroradiology · 2015Article
- Sentinel lymph node biopsy in oral and oropharyngeal squamous cell carcinoma: current status and unresolved challenges.European journal of nuclear medicine and molecular imaging · 2015Review
- The next evolution in radioguided surgery: breast cancer related sentinel node localization using a freehandSPECT-mobile gamma camera combination.American journal of nuclear medicine and molecular imaging · 2015Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to prospectively evaluate the feasibility and potential advantages of freehand single-photon emission computed tomography (fhSPECT) compared with conventional intraoperative localization techniques for sentinel lymph node biopsy (SLNB) in oral cancer.
methodsBetween November 2012 and February 2014, 23 consecutive patients with clinical T1/T2 oral squamous cell carcinoma and a cN0 neck were recruited. All patients underwent SLNB followed by elective neck dissection (END). All patients received preoperative lymphoscintigraphy. To detect the SLNs intraoperatively, fhSPECT with a combination of conventional acoustic SLN localization and 3-D visual navigation was used.
resultsAll but one of the SLNs detected by preoperative imaging were successfully mapped intraoperatively by fhSPECT (detection rate 98%), including those in six patients with a tumour in the floor of the mouth. A histopathology analysis revealed positive SLNs in 22% of patients. No further metastases were found in LNs resected during END. SLNB correctly predicted the final LN stage in all patients (accuracy 100%). Additional radioactive LNs, which were not present on preoperative lymphoscintigraphy, were observed in three patients.
conclusionFhSPECT is a feasible technology that allows the accurate identification of SLNs in oral cancer. FhSPECT overcomes the shine-through phenomenon, one of the most important limitations of SLNB, thereby confirming the importance of SLNB in patients with cN0 oral cancer.
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