Evidence map›Paper›PMID 25077142›Full record

ReviewFrontiers in chemistry2014

Revisiting 30 years of biofunctionalization and surface chemistry of inorganic nanoparticles for nanomedicine.

João Conde, Jorge T Dias, Valeria Grazú, Maria Moros, Pedro V Baptista, Jesus M de la Fuente

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed.

  1. Article
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  3. Functionalized AgFeOACS omega · 2026
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  10. Targeted delivery of peptide functionalized nanoparticles for ameliorating myocardial infarction.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  11. Article
  12. Review
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  15. Article
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  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

João CondeHarvard-MIT Division for Health Sciences and Technology, Institute for Medical Engineering and Science, Massachusetts Institute of Technology Cambridge, MA, USA.
Jorge T DiasNanotherapy and Nanodiagnostics Group, Instituto de Nanociencia de Aragon, Universidad de Zaragoza Zaragoza, Spain.
Valeria GrazúNanotherapy and Nanodiagnostics Group, Instituto de Nanociencia de Aragon, Universidad de Zaragoza Zaragoza, Spain.
Maria MorosNanotherapy and Nanodiagnostics Group, Instituto de Nanociencia de Aragon, Universidad de Zaragoza Zaragoza, Spain.
Pedro V BaptistaCIGMH, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa Caparica, Portugal.
Jesus M de la FuenteNanotherapy and Nanodiagnostics Group, Instituto de Nanociencia de Aragon, Universidad de Zaragoza Zaragoza, Spain ; Fundacion ARAID Zaragoza, Spain ; Key Laboratory for Thin Film and Microfabrication Technology of the Ministry of Education, Department of Bio-Nano Science and Engineering, Institute of Nano Biomedicine and Engineering, Research Institute of Translation Medicine, Shanghai Jiao Tong University Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last 30 years we have assisted to a massive advance of nanomaterials in material science. Nanomaterials and structures, in addition to their small size, have properties that differ from those of larger bulk materials, making them ideal for a host of novel applications. The spread of nanotechnology in the last years has been due to the improvement of synthesis and characterization methods on the nanoscale, a field rich in new physical phenomena and synthetic opportunities. In fact, the development of functional nanoparticles has progressed exponentially over the past two decades. This work aims to extensively review 30 years of different strategies of surface modification and functionalization of noble metal (gold) nanoparticles, magnetic nanocrystals and semiconductor nanoparticles, such as quantum dots. The aim of this review is not only to provide in-depth insights into the different biofunctionalization and characterization methods, but also to give an overview of possibilities and limitations of the available nanoparticles.

Indexed as

biofunctionalizationchemistry surfacegold nanoparticlesmagnetic nanoparticlesquantum dots

Identifiers

PMID25077142
PMCPMC4097105

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.