Evidence map›Paper›PMID 25077137›Full record

ArticleFrontiers in public health2014

HIV-Infected Individuals Who Delay, Decline, or Discontinue Antiretroviral Therapy: Comparing Clinic- and Peer-Recruited Cohorts.

Marya Gwadz, Elizabeth Applegate, Charles Cleland, Noelle Regina Leonard, Hannah Wolfe, Nadim Salomon, Mindy Belkin, Marion Riedel, Angela Banfield, Lisa Sanfilippo and 3 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Barriers to Rapid Enrollment and ART Initiation Among U.S. HIV Care Facilities.Journal of acquired immune deficiency syndromes (1999) · 2025
    Article
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  5. Article
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  15. Population-Based Estimates of Life Expectancy After HIV Diagnosis: United States 2008-2011.Journal of acquired immune deficiency syndromes (1999) · 2016
    Article
  16. Article
  17. Observational
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marya GwadzCenter for Drug Use and HIV Research (CDUHR), New York University, College of Nursing , New York, NY , USA.
Elizabeth ApplegateCenter for Drug Use and HIV Research (CDUHR), New York University, College of Nursing , New York, NY , USA.
Charles ClelandCenter for Drug Use and HIV Research (CDUHR), New York University, College of Nursing , New York, NY , USA.
Noelle Regina LeonardCenter for Drug Use and HIV Research (CDUHR), New York University, College of Nursing , New York, NY , USA.
Hannah WolfeSpencer Cox Center for Health, Mount Sinai St. Luke's-Roosevelt Hospital Center , New York, NY , USA.
Nadim SalomonPeter Kruger Clinic, Mount Sinai Beth Israel Medical Center , New York, NY , USA.
Mindy BelkinCenter for Drug Use and HIV Research (CDUHR), New York University, College of Nursing , New York, NY , USA.
Marion RiedelSchool of Social Work, Columbia University , New York, NY , USA.
Angela BanfieldCenter for Drug Use and HIV Research (CDUHR), New York University, College of Nursing , New York, NY , USA.
Lisa SanfilippoCenter for Drug Use and HIV Research (CDUHR), New York University, College of Nursing , New York, NY , USA.
Andrea WagnerCenter for Drug Use and HIV Research (CDUHR), New York University, College of Nursing , New York, NY , USA.
Donna MildvanDepartment of Infectious Diseases, Mount Sinai Beth Israel Medical Center , New York, NY , USA.
Heart to Heart Collaborative Research Team

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan · 1998 to 2026
$38.9M
Intervention to Increase Timely Initiation of HAART Among Those Who Delay/DeclineR34MH093352 · NIMH · NEW YORK UNIVERSITY · PI GWADZ, MARYA · 2011 to 2013
$685k
NIDA NIH HHS P30 DA011041NIMH NIH HHS R34 MH093352
6 · The paper itself

Abstract

A substantial proportion of persons living with HIV/AIDS (PLHA) delay, decline, or discontinue antiretroviral therapy (ART) when it is medically indicated (40-45%), largely African-Americans and Latinos/Hispanics. This study explores the feasibility of locating PLHA, who are not on ART (PLHA-NOA) through clinics and peer-referral; compares the two cohorts on multi-level barriers to ART; and examines readiness to initiate/reinitiate ART, a predictor of treatment outcomes. We recruited adult HIV-infected African-American and Latino/Hispanic PLHA-NOA through HIV hospital clinics and peer-referral in 2012-2013. Participants were engaged in structured 1-h assessments with reliable/valid measures on barriers to ART. We found that recruitment through peers (63.2%, 60/95) was more feasible than in clinics (36.8%, 35/90). Participants were 48.0 years old and had lived with HIV for 14.7 years on average, and 56.8% had taken ART previously. Most (61.1%) were male and African-American (76.8%), and 23.2% were Latino/Hispanic. Peer-recruited participants were older, had lived with HIV longer, were less engaged in HIV care, and were more likely to have taken ART previously. The cohorts differed in reasons for discontinuing ART. Levels of ART knowledge were comparable between cohorts (68.5% correct), and there were no differences in attitudes toward ART (e.g., mistrust), which were in the neutral range. In bivariate linear regression, readiness for ART was negatively associated with physician mistrust (B = -10.4) and positively associated with self-efficacy (B = 5.5), positive outcome expectancies (B = 6.3), beliefs about personal necessity of ART (B = 17.5), and positive internal norms (B = 7.9). This study demonstrates the feasibility of engaging this vulnerable population through peer-referral. Peer-recruited PLHA evidence particularly high rates of risk factors compared to those in hospital clinics. Interventions to support ART initiation and continuation are sorely needed for both subgroups.

Indexed as

African-AmericanantiretroviralbarriersdeclinedelaydiscontinueHIVLatino

Identifiers

PMID25077137
PMCPMC4100062

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.