Evidence map›Paper›PMID 25077072›Full record

ReviewFrontiers in cellular and infection microbiology2014

Small RNA functions in carbon metabolism and virulence of enteric pathogens.

Kai Papenfort, Jörg Vogel

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 121 citations in OpenAlex.

  1. Article
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  4. Article
  5. Review
  6. Article
  7. tRNA epitranscriptome determines pathogenicity of the opportunistic pathogenProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Sense and antisense RNA products of theFrontiers in molecular biosciences · 2023
    Article
  9. Small regulatory RNAs inmicroLife · 2023
    Review
  10. Article
  11. Article
  12. Dual-function AzuCR RNA modulates carbon metabolism.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Review
  14. TheFrontiers in molecular biosciences · 2022
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kai PapenfortDepartment of Molecular Biology, Princeton University Princeton, NJ, USA.
Jörg VogelRNA Biology Group, Institute for Molecular Infection Biology, University of Würzburg Würzburg, Germany.
Princeton University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteric pathogens often cycle between virulent and saprophytic lifestyles. To endure these frequent changes in nutrient availability and composition bacteria possess an arsenal of regulatory and metabolic genes allowing rapid adaptation and high flexibility. While numerous proteins have been characterized with regard to metabolic control in pathogenic bacteria, small non-coding RNAs have emerged as additional regulators of metabolism. Recent advances in sequencing technology have vastly increased the number of candidate regulatory RNAs and several of them have been found to act at the interface of bacterial metabolism and virulence factor expression. Importantly, studying these riboregulators has not only provided insight into their metabolic control functions but also revealed new mechanisms of post-transcriptional gene control. This review will focus on the recent advances in this area of host-microbe interaction and discuss how regulatory small RNAs may help coordinate metabolism and virulence of enteric pathogens.

Indexed as

Energy MetabolismAnimalsCarbonChitinC-Reactive ProteinEnterobacteriaceaeGene Expression Regulation, BacterialGlucoseHomeostasisHost Factor 1 ProteinHost-Pathogen InteractionsHumansIntestinesRNA, BacterialRNA-Binding ProteinsRNA, Small UntranslatedCarbonChitinC-Reactive ProteinGlucoseHost Factor 1 ProteinRNA, BacterialRNA-Binding ProteinsRNA, Small UntranslatedVirulence Factorscarbon metabolismCsrAHfqsRNAvirulence

Identifiers

PMID25077072
PMCPMC4098024
OpenAlexW2038219941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.