ArticleEcology and evolution2014
Different degree of paternal mtDNA leakage between male and female progeny in interspecific Drosophila crosses.
Article in Ecology and evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Paternal leakage of mitochondrial DNA is genetically controlled in Drosophila.G3 (Bethesda, Md.) · 2026Article
- Evidence for Paternal Mitochondrial DNA Leakage in Diploid Hybrid Fish Lineages.Animals : an open access journal from MDPI · 2026Article
- Pervasive non-random mitochondrial DNA heteroplasmy in the hybrid water frog Pelophylax esculentus.BMC ecology and evolution · 2025Article
- Pervasive heteroplasmy in an invasive ambrosia beetle (Scolytinae) in southern California.Heredity · 2024Article
- Mitochondrial Differentiation during Spermatogenesis: Lessons fromInternational journal of molecular sciences · 2024Review
- Maternal mitochondrial function affects paternal mitochondrial inheritance in Drosophila.Genetics · 2024Article
- Convergent Mutations and Single Nucleotide Variants in Mitochondrial Genomes of Modern Humans and Neanderthals.International journal of molecular sciences · 2024Article
- Evidence for hybridization-driven heteroplasmy maintained across generations in a ricefish endemic to a Wallacean ancient lake.Biology letters · 2024Article
- Mother's Curse effects on lifespan and aging.Frontiers in aging · 2024Review
- The gender-specific impact of starvation on mitotypes diversity in adults ofOpen biology · 2022Article
- Article
- mtDNA Heteroplasmy: Origin, Detection, Significance, and Evolutionary Consequences.Life (Basel, Switzerland) · 2021Review
- Paternal leakage of mitochondrial DNA and maternal inheritance of heteroplasmy in Drosophila hybrids.Scientific reports · 2020Article
- High incidence of heteroplasmy in the mtDNA of a natural population of the spider crab Maja brachydactyla.PloS one · 2020Article
- Article
- Evidence for the paternal mitochondrial DNA in the crucian carp-like fish lineage with hybrid origin.Science China. Life sciences · 2020Article
- Mitophagy: An Emerging Role in Aging and Age-Associated Diseases.Frontiers in cell and developmental biology · 2020Review
- Ancient hybridization and mtDNA introgression behind current paternal leakage and heteroplasmy in hybrid zones.Scientific reports · 2019Article
- Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy.Cell metabolism · 2019Article
- Mitochondrial heteroplasmy in an avian hybrid form (Mitochondrial DNA. Part B, Resources · 2019Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Maternal transmission of mitochondrial DNA (mtDNA) in animals is thought to prevent the spread of selfish deleterious mtDNA mutations in the population. Various mechanisms have been evolved independently to prevent the entry of sperm mitochondria in the embryo. However, the increasing number of instances of paternal mtDNA leakage suggests that these mechanisms are not very effective. The destruction of sperm mitochondria in mammalian embryos is mediated by nuclear factors. Also, the destruction of paternal mitochondria in intraspecific crosses is more effective than in interspecific ones. These observations have led to the hypothesis that leakage of paternal mtDNA (and consequently mtDNA recombination owing to ensuing heteroplasmy) might be more common in inter- than in intraspecific crosses and that it should increase with phylogenetic distance of hybridizing species. We checked paternal leakage in inter- and intraspecific crosses in Drosophila and found little evidence for this hypothesis. In addition, we have observed a higher level of leakage among male than among female progeny from the same cross. This is the first report of sex-specific leakage of paternal mtDNA. It suggests that paternal mtDNA leakage might not be a stochastic result of an error-prone mechanism, but rather, it may be under complex genetic control.
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