Evidence map›Paper›PMID 25076887›Full record

ReviewFrontiers in neuroengineering2014

Neuromodulation: present and emerging methods.

Song Luan, Ian Williams, Konstantin Nikolic, Timothy G Constandinou

Abstract readReview
In one paragraph

Review in Frontiers in neuroengineering, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effects of home-based neurostimulation on outcomes after stroke: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
  2. Novel Extranasal Tear Stimulation: Pivotal Study Results.Translational vision science & technology · 2020
    Trial
  3. Article
  4. Article
  5. Article
  6. Illuminating consciousness.Frontiers in psychology · 2026
    Review
  7. Single-Molecule Vibrational Thermometry.The journal of physical chemistry. B · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Cerebellar Purkinje Cell Activity Regulates White Matter Response and Locomotor Function after Neonatal Hypoxia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  12. Review
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Song LuanDepartment of Electrical and Electronic Engineering, Imperial College London London, UK ; Center for Bio-Inspired Technology, Institute of Biomedical Engineering, Imperial College London London, UK.
Ian WilliamsDepartment of Electrical and Electronic Engineering, Imperial College London London, UK ; Center for Bio-Inspired Technology, Institute of Biomedical Engineering, Imperial College London London, UK.
Konstantin NikolicDepartment of Electrical and Electronic Engineering, Imperial College London London, UK ; Center for Bio-Inspired Technology, Institute of Biomedical Engineering, Imperial College London London, UK.
Timothy G ConstandinouDepartment of Electrical and Electronic Engineering, Imperial College London London, UK ; Center for Bio-Inspired Technology, Institute of Biomedical Engineering, Imperial College London London, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Neuromodulation has wide ranging potential applications in replacing impaired neural function (prosthetics), as a novel form of medical treatment (therapy), and as a tool for investigating neurons and neural function (research). Voltage and current controlled electrical neural stimulation (ENS) are methods that have already been widely applied in both neuroscience and clinical practice for neuroprosthetics. However, there are numerous alternative methods of stimulating or inhibiting neurons. This paper reviews the state-of-the-art in ENS as well as alternative neuromodulation techniques-presenting the operational concepts, technical implementation and limitations-in order to inform system design choices.

Indexed as

neural modulationneural prosthesisneural stimulationneuromodulationneuroprostheticsneurostimulation

Identifiers

PMID25076887
PMCPMC4097946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.