Evidence map›Paper›PMID 25075788›Full record

ArticleMemorias do Instituto Oswaldo Cruz2014

A four-year surveillance program for detection of Plasmodium falciparum chloroquine resistance in Honduras.

Gustavo A Fontecha, Ana L Sanchez, Meisy Mendoza, Engels Banegas, Rosa E Mejía-Torres

Abstract read
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Molecular Characterization ofTropical medicine and infectious disease · 2025
    Article
  2. Genetic diversity ofCurrent research in parasitology & vector-borne diseases · 2025
    Article
  3. The human malaria-Antimicrobial agents and chemotherapy · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Establishing a National Molecular Surveillance Program for the Detection ofThe American journal of tropical medicine and hygiene · 2020
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gustavo A FontechaMicrobiology Research Institute, National Autonomous University of Honduras, Tegucigalpa, Honduras.
Ana L SanchezDepartment of Health Sciences, Faculty of Applied Health Sciences, Brock University, Saint Catharines, ON, Canada.
Meisy MendozaNational Malaria Laboratory, National Department of Surveillance, Ministry of Health-Honduras, Tegucigalpa, Honduras.
Engels BanegasNational Malaria Program, Department of Health Promotion, Ministry of Health-Honduras, Tegucigalpa, Honduras.
Rosa E Mejía-TorresPanamerican Health Organization-Honduras, Tegucigalpa, Honduras.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Countries could use the monitoring of drug resistance in malaria parasites as an effective early warning system to develop the timely response mechanisms that are required to avert the further spread of malaria. Drug resistance surveillance is essential in areas where no drug resistance has been reported, especially if neighbouring countries have previously reported resistance. Here, we present the results of a four-year surveillance program based on the sequencing of the pfcrt gene of Plasmodium falciparum populations from endemic areas of Honduras. All isolates were susceptible to chloroquine, as revealed by the pfcrt "CVMNK" genotype in codons 72-76.

Indexed as

AntimalarialsChloroquineDNA, ProtozoanDrug ResistanceGenotypeHondurasHumansPlasmodium falciparumPopulation SurveillanceProtozoan ProteinsAntimalarialsChloroquineDNA, ProtozoanProtozoan Proteins

Identifiers

PMID25075788
PMCPMC4155854

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.