ArticleMemorias do Instituto Oswaldo Cruz2014
Acute gastroenteritis and enteric viruses in hospitalised children in southern Brazil: aetiology, seasonality and clinical outcomes.
Article in Memorias do Instituto Oswaldo Cruz, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Human adenoviruses in children with gastroenteritis: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- Hidden Circulation and Socio-Sanitary Vulnerability: Rotavirus A and Human Adenovirus Prevalence in Symptomatic and Asymptomatic Children in Central Brazil Post-COVID-19.Pathogens (Basel, Switzerland) · 2025Article
- A Multi-Pathogen Retrospective Study in Patients Hospitalized for Acute Gastroenteritis.Diseases (Basel, Switzerland) · 2024Article
- Article
- Molecular analysis of adenovirus strains responsible for gastroenteritis in children, under five, in Tunisia.Heliyon · 2024Article
- Surveillance and epidemiological characterization of human adenovirus infections among outpatient children with acute gastroenteritis during the COVID-19 epidemic in Shanghai, China.Virology journal · 2023Article
- Prevalence, Clinical Severity, and Seasonality of Adenovirus 40/41, Astrovirus, Sapovirus, and Rotavirus Among Young Children With Moderate-to-Severe Diarrhea: Results From the Vaccine Impact on Diarrhea in Africa (VIDA) Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Article
- Human enteric adenovirus F40/41 as a major cause of acute gastroenteritis in children in Brazil, 2018 to 2020.Scientific reports · 2022Article
- Viral pathogens of acute gastroenteritis in Egyptian children: role of the parechovirus.BMC infectious diseases · 2022Article
- Nonenteric Adenoviruses Associated with Gastroenteritis in Hospitalized Children.Microbiology spectrum · 2021Article
- Diversity of enteric and non-enteric human adenovirus strains in Brazil, 2006-2011.Archives of virology · 2021Article
- Analysis of viral diversity in stool samples from infants and children with acute gastroenteritis in Kuwait using Metagenomics approach.Virology journal · 2020Article
- Adenovirus and rotavirus recovery from a treated effluent through an optimized skimmed-milk flocculation method.Environmental science and pollution research international · 2018Article
- Norovirus RNA in serum associated with increased fecal viral load in children: Detection, quantification and molecular analysis.PloS one · 2018Observational
- Rotavirus vaccination takes seasonal signature of childhood diarrhea back to pre-sanitation era in Brazil.The Journal of infection · 2018Article
- Norovirus epidemiology in South African children <5 years hospitalised for diarrhoeal illness between 2009 and 2013.Epidemiology and infection · 2017Article
- Recent viral pathogen in acute gastroenteritis: a retrospective study at a tertiary hospital for 1 year.Korean journal of pediatrics · 2016Article
- Community-Acquired Rotavirus Gastroenteritis Compared with Adenovirus and Norovirus Gastroenteritis in Italian Children: A Pedianet Study.International journal of pediatrics · 2016Article
- Relationship between viral detection and turbidity in a watershed contaminated with group A rotavirus.Environmental science and pollution research international · 2015Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Viral acute gastroenteritis (AG) is a significant cause of hospitalisation in children younger than five years. Group A rotavirus (RVA) is responsible for 30% of these cases. Following the introduction of RVA immunisation in Brazil in 2006, a decreased circulation of this virus has been observed. However, AG remains an important cause of hospitalisation of paediatric patients and only limited data are available regarding the role of other enteric viruses in these cases. We conducted a prospective study of paediatric patients hospitalised for AG. Stool samples were collected to investigate human adenovirus (HAdV), RVA, norovirus (NoV) and astrovirus (AstV). NoV typing was performed by nucleotide sequencing and phylogenetic analysis. From the 225 samples tested, 60 (26%) were positive for at least one viral agent. HAdV, NoV, RVA and AstV were detected in 16%, 8%, 6% and 0% of the samples, respectively. Mixed infections were found in nine patients: HAdV/RVA (5), HAdV/NoV (3) and HAdV/NoV/RVA (1). The frequency of fever and lymphocytosis was significantly higher in virus-infected patients. Phylogenetic analysis of NoV indicated that all of these viruses belonged to genotype GII.4. The significant frequency of these pathogens in patients with AG highlights the need to routinely implement laboratory investigations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.