Evidence map›Paper›PMID 25075261›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2013

Radiant energy during infrared neural stimulation at the target structure.

Claus-Peter Richter, Suhrud Rajguru, Ryan Stafford, Stuart R Stock

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. A review of optical pacing with infrared light.Journal of neural engineering · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Claus-Peter RichterDepartment of Otolaryngology, Northwestern University, 303 E. Chicago Ave, Searle 12-561, Chicago, IL 60611, USA ; Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Tech E310, Evanston, IL 60208, USA ; The Hugh Knowles Center, Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL 60208, USA.
Suhrud RajguruDepartment of Biomedical Engineering, University of Miami, Miami FL 33146, USA ; Department of Otolaryngology, University of Miami, Miami FL 33136, USA.
Ryan StaffordLockheed Martin Aculight, 22121 20th Ave SE, Bothell WA, USA.
Stuart R StockDepartment of Molecular Pharmacology and Biological Chemistry, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

Funding

Understanding the Benefits of Infrared Nerve Stimulators for Neural InterfacesR01DC011855 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RICHTER, CLAUS-PETER · 2012 to 2016
$2.4M
Infrared Photoactivation of Inner-Ear Hair CellsR01DC011481 · NIDCD · MARINE BIOLOGICAL LABORATORY · PI RABBITT, RICHARD D · 2011 to 2013
$984k
NIDCD NIH HHS R01 DC011481NIDCD NIH HHS R01 DC011855
6 · The paper itself

Abstract

Infrared neural stimulation (INS) describes a method, by which an infrared laser is used to stimulate neurons. The major benefit of INS over stimulating neurons with electrical current is its spatial selectivity. To translate the technique into a clinical application it is important to know the energy required to stimulate the neural structure. With this study we provide measurements of the radiant exposure, at the target structure that is required to stimulate the auditory neurons. Flat polished fibers were inserted into scala tympani so that the spiral ganglion was in front of the optical fiber. Angle polished fibers were inserted along scala tympani, and rotating the beveled surface of the fiber allowed the radiation beam to be directed perpendicular to the spiral ganglion. The radiant exposure for stimulation at the modiolus for flat and angle polished fibers averaged 6.78±2.15 mJ/cm

Indexed as

cochleahearinginfrared neural stimulationlaseroptical stimulation

Identifiers

PMID25075261
PMCPMC4112115

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.