Evidence map›Paper›PMID 25074830›Full record

ArticleEnvironmental science and pollution research international2015

Co-exposure of arsenic and cadmium through drinking water and tobacco smoking: risk assessment on kidney dysfunction.

Muhammad B Arain, Tasneem G Kazi, Jameel Ahmed Baig, Hassan I Afridi, Sarajuddin, Kapil D Brehman, Haleem Panhwar, Sadaf S Arain

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Association of Combined Per- and Polyfluoroalkyl Substances and Metals with Chronic Kidney Disease.International journal of environmental research and public health · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Emerging role of air pollution in chronic kidney disease.Environmental science and pollution research international · 2021
    Review
  9. Article
  10. Cadmium in soils and groundwater: A review.Applied geochemistry : journal of the International Association of Geochemistry and Cosmochemistry · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Muhammad B ArainDepartment of Chemistry, Abdul Wali Khan University Mardan, Mardan, 23200, KP., Pakistan, bilal_ku2004@yahoo.com.
Tasneem G Kazi
Jameel Ahmed Baig
Hassan I Afridi
Sarajuddin
Kapil D Brehman
Haleem Panhwar
Sadaf S Arain
University of Sindh · PKNational Centre of Excellence in Analytical Chemistry · PKAbdul Wali Khan University Mardan · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combined exposure of arsenic (As) and cadmium (Cd) causes more pronounced renal toxicity. The study aimed to evaluate the level of As and Cd in biological samples (blood and urine) of adults males, age ranged (30-50 years) exposed referent (ER) and exposed kidney patients (EKP), consumed contaminated drinking water of lake and smoking local cigarettes manufactured by tobacco plants grown on agricultural soil, irrigated with contaminated lake water. For comparative purpose age matched nonexoposed referent (NR) and nonexposed kidney patient (NKP), consumed municipal treaded water and smoking branded cigarette were also selected. The As and Cd levels in drinking water, biological samples, tobacco of branded and nonbranded cigarettes were analyzed using electrothermal atomic absorption spectrometry. The As and Cd concentrations in lake water were higher than the permissible limit recommended by the World Health Organization for drinking water. The As and Cd levels in local cigarette tobacco were found to be 3- to 4-folds higher than branded cigarettes. The biochemical parameters especially urinary N-acetyl-β-glucosaminidase (NAG) of ER, EKP, ER, and EKP subjects were studied as a biomarkers of renal dysfunction. The NAG values were found to be higher in EKP as compared to NKP (p < 0.01). The linear regressions showed higher correlations between As and Cd concentrations in water versus blood and urine samples of EKP (r = 0.71-0.78 and 0.68-0.72), as compared to NKP (p < 0.05).

Indexed as

Environmental ExposureAdultArsenicBiomarkersCadmiumCase-Control StudiesDrinking WaterHumansKidneyKidney DiseasesLakesMaleMiddle AgedNicotianaRisk AssessmentSmokingArsenicBiomarkersCadmiumDrinking WaterWater Pollutants, Chemical

Identifiers

PMID25074830
OpenAlexW1978897247

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.