Evidence map›Paper›PMID 25074707›Full record

ArticleElectrophoresis2015

Nanopore back titration analysis of dipicolinic acid.

Yujing Han, Shuo Zhou, Liang Wang, Xiyun Guan

Abstract read
In one paragraph

Article in Electrophoresis, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  9. Probe-assisted detection of FeBiosensors & bioelectronics · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Label-Free Detection of DNA Mutations by Nanopore Analysis.ACS applied materials & interfaces · 2018
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yujing HanDepartment of Biological and Chemical Sciences, Illinois Institute of Technology, Chicago, IL, USA.
Shuo Zhou
Liang Wang
Xiyun Guan
Illinois Institute of Technology · US

Funding

Label-Free Nanopore Biosensor for Rapid, Ultrasensitive, and Multiplex Detection of Protease ActivitiesR15GM110632 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI GUAN, XIYUN · 2014 to 2017
$746k
NIGMS NIH HHS R15 GM110632
6 · The paper itself

Abstract

Here, we report a novel label-free nanopore back titration method for the detection of dipicolinic acid, a marker molecule for bacterial spores. By competitive binding of the target analyte and a large ligand probe to metal ions, dipicolinic acid could be sensitively and selectively detected. This nanopore back titration approach should find useful applications in the detection of other species of medical, biological, or environmental importance if their direct detection is difficult to achieve.

Indexed as

NanoporesBacteriological TechniquesBiomarkersPicolinic AcidsSpores, BacterialTerbiumTitrimetryBiomarkersdipicolinic acidPicolinic AcidsTerbiumBack titrationDipicolinic acidLabel-freeNanoporeTerbium

Identifiers

PMID25074707
PMCPMC4511083
OpenAlexW1480844700

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.