ArticleJournal of the American Heart Association2014
Non-ST-elevation myocardial infarction in the United States: contemporary trends in incidence, utilization of the early invasive strategy, and in-hospital outcomes.
Article in Journal of the American Heart Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review and meta-analysis of percutaneous coronary intervention compared to coronary artery bypass grafting in non-ST-elevation acute coronary syndrome.Scientific reports · 2022Pooled it
- Pulmonary artery catheterization in patients with cardiogenic shock: a systematic review and meta-analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Pooled it
- Sex Differences in Characteristics, Treatments, and Outcomes Among Patients Hospitalized for Non-ST-Segment-Elevation Myocardial Infarction in China: 2006 to 2015.Circulation. Cardiovascular quality and outcomes · 2022Trial
- Age-stratified trends in myocardial infarction subtype composition among U.S. adults.Internal and emergency medicine · 2026Article
- Coronary revascularisation in British Columbia: 25-year trends in volume and modality.General thoracic and cardiovascular surgery · 2026Article
- Predicting Contrast-Induced Nephropathy in NSTEMI: The Role of the HALP Score.Medicina (Kaunas, Lithuania) · 2025Article
- Observational analysis of non-ST-segment elevation myocardial infarction invasive management and mortality over the decades.Open heart · 2025Observational
- Article
- Age and sex differences in the efficacy of early invasive strategy for non-ST-elevation acute coronary syndrome: A comparative analysis in stable patients.American journal of preventive cardiology · 2025Article
- Article
- Early coronary revascularization among 'stable' patients with non-ST-segment elevation acute coronary syndromes: the role of diabetes and age.Cardiovascular research · 2024Article
- Hypothermia for Cardioprotection in Acute Coronary Syndrome Patients: From Bench to Bedside.Journal of clinical medicine · 2024Review
- Platelet Glycoprotein IIIaJournal of clinical medicine research · 2024Article
- Mortality in Patients with Acute Coronary Syndrome-A Prospective 5-Year Follow-Up Study.Journal of clinical medicine · 2023Article
- Declining risk of heart failure hospitalization following first acute myocardial infarction in Scotland between 1991-2016.European journal of heart failure · 2023Article
- Article
- The impact of on-site cardiac surgical backup on clinical outcomes of acute coronary syndrome-analysis of the ACSIS national registry.Frontiers in cardiovascular medicine · 2023Article
- Myocardial infarction and physical function: the REasons for Geographic And Racial Differences in Stroke prospective cohort study.BMJ public health · 2023Article
- Impact of ST-Segment-Elevation Myocardial Infarction Regionalization Programs on the Treatment and Outcomes of Patients Diagnosed With Non-ST-Segment-Elevation Myocardial Infarction.Journal of the American Heart Association · 2021Article
- Multivessel versus IRA-only PCI in patients with NSTEMI and severe left ventricular systolic dysfunction.PloS one · 2021Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere has been a paradigm shift in the definition of timing of early invasive strategy (EIS) for patients admitted with non-ST-elevation myocardial infarction (NSTEMI) in the last decade. Data on trends of EIS for NSTEMI and associated in-hospital outcomes are limited. Our aim is to analyze temporal trends in the incidence, utilization of early invasive strategy, and in-hospital outcomes of NSTEMI in the United States. METHODS AND
resultsWe analyzed the 2002-2011 Nationwide Inpatient Sample databases to identify all patients ≥40 years of age with the principal diagnosis of acute myocardial infarction (AMI) and NSTEMI. Logistic regression was used for overall, age-, sex-, and race/ethnicity-stratified trend analysis. From 2002 to 2011, we identified 6 512 372 patients with AMI. Of these, 3 981 119 (61.1%) had NSTEMI. The proportion of patients with NSTEMI increased from 52.8% in 2002 to 68.6% in 2011 (adjusted odds ratio [OR; per year], 1.055; 95% confidence interval [CI], 1.054 to 1.056) in the overall cohort. Similar trends were observed in age-, sex-, and race/ethnicity-stratified groups. From 2002 to 2011, utilization of EIS at day 0 increased from 14.9% to 21.8% (Ptrend<0.001) and utilization of EIS at day 0 or 1 increased from 27.8% to 41.4% (Ptrend<0.001). Risk-adjusted in-hospital mortality in the overall cohort decreased during the study period (adjusted OR [per year], 0.976; 95% CI, 0.974 to 0.978).
conclusionsThere have been temporal increases in the proportion of NSTEMI and, consistent with guidelines, greater utilization of EIS. This has been accompanied by temporal decreases in in-hospital mortality and length of stay.
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