Trial reportEuropean journal of applied physiology2014
The effect of various cold-water immersion protocols on exercise-induced inflammatory response and functional recovery from high-intensity sprint exercise.
Trial report in European journal of applied physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Pooled it
- Impact of different doses of cold water immersion (duration and temperature variations) on recovery from acute exercise-induced muscle damage: a network meta-analysis.Frontiers in physiology · 2025Pooled it
- Effects of cold water immersion after exercise on fatigue recovery and exercise performance--meta analysis.Frontiers in physiology · 2023Pooled it
- Impact of Cold-Water Immersion Compared with Passive Recovery Following a Single Bout of Strenuous Exercise on Athletic Performance in Physically Active Participants: A Systematic Review with Meta-analysis and Meta-regression.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Cold Water Immersion Does Not Enhance Recovery and Performance After High-Intensity Interval Dorsiflexion Exercise.Scandinavian journal of medicine & science in sports · 2025Trial
- Exploring the Influence of Acid-Base Status on Athletic Performance during Simulated Three-Day 400 m Race.Nutrients · 2024Trial
- Partial-body cryotherapy (-135°C) and cold-water immersion (10°C) after muscle damage in females.Scandinavian journal of medicine & science in sports · 2020Trial
- Multiple Cold-Water Immersions Attenuate Muscle Damage but not Alter Systemic Inflammation and Muscle Function Recovery: A Parallel Randomized Controlled Trial.Scientific reports · 2018Trial
- Recovery following a marathon: a comparison of cold water immersion, whole body cryotherapy and a placebo control.European journal of applied physiology · 2018Trial
- Effects of Cold Water Immersion on Muscle Oxygenation During Repeated Bouts of Fatiguing Exercise: A Randomized Controlled Study.Medicine · 2016Trial
- 21 days of mammalian omega-3 fatty acid supplementation improves aspects of neuromuscular function and performance in male athletes compared to olive oil placebo.Journal of the International Society of Sports Nutrition · 2015Trial
- Cold Water Immersion or Foam Rolling? A Randomized Crossover Trial Comparing Recovery Effects on High-Intensity Performance and Markers of Muscle Damage and Inflammation in Soccer Players.Sports (Basel, Switzerland) · 2026Article
- Cold water immersion protocol optimization across exercise modalities: a systematic review and network meta-analysis of resistance training, endurance exercise, and team sport applications.BMC sports science, medicine & rehabilitation · 2026Article
- Effects of cold-water immersion at different body regions on post-exercise muscle damage recovery: a systematic review and meta-analysis.Frontiers in sports and active living · 2026Review
- Using Force Plates to Monitor the Recovery of Vertical Jump Performance After Strenuous Exercise: A Systematic Review and Meta-Analysis.Journal of functional morphology and kinesiology · 2025Review
- Comparative Efficacy of Vibration foam Rolling and Cold Water Immersion in Amateur Basketball Players after a Simulated Load of Basketball Game.Healthcare (Basel, Switzerland) · 2023Article
- Effects of cold water immersion and protein intake combined recovery after eccentric exercise on exercise performance in elite soccer players.Journal of exercise rehabilitation · 2023Article
- The Influence of Winter Swimming on Oxidative Stress Indicators in the Blood of Healthy Males.Metabolites · 2023Article
- Cold water immersion after a soccer match: Does the placebo effect occur?Frontiers in physiology · 2023Article
- The Influence of Ambient Temperature Changes on the Indicators of Inflammation and Oxidative Damage in Blood after Submaximal Exercise.Antioxidants (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to investigate the effects of different cold-water immersion (CWI) protocols on the inflammatory response to and functional recovery from high-intensity exercise.
methodsEight healthy recreationally active males completed five trials of a high-intensity intermittent sprint protocol followed by a randomly assigned recovery condition: 1 of 4 CWI protocols (CWI-10 min × 20 °C, CWI-30 min × 20 °C, CWI-10 min × 10 °C, or CWI-30 min × 10 °C) versus passive rest. Circulating mediators of the inflammatory response were measured from EDTA plasma taken pre-exercise (baseline), immediately post-exercise, and at 2, 24, and 48 h post-exercise. Ratings of perceived soreness and impairment were noted on a 10-pt Likert scale, and squat jump and drop jump were performed at these time points.
resultsIL-6, IL-8, and MPO increased significantly from baseline immediately post-exercise in all conditions. IL-6 remained elevated from baseline at 2 h in the CWI-30 min × 20 °C, CWI-10 min × 10 °C, and CWI-30 min × 10 °C conditions, while further increases were observed for IL-8 and MPO in the CWI-30 min × 20 °C and CWI-30 min × 10 °C conditions. Squat jump and drop jump height were significantly lower in all conditions immediately post-exercise and at 2 h. Drop jump remained below baseline at 24 and 48 h in the CON and CWI-10 min × 20 °C conditions only, while squat jump height returned to baseline in all conditions.
conclusionsCold-water immersion appears to facilitate restoration of muscle performance in a stretch-shortening cycle, but not concentric power. These changes do not appear to be related to inflammatory modulation. CWI protocols of excessive duration may actually exacerbate the concentration of cytokines in circulation post-exercise; however, the origin of the circulating cytokines is not necessarily skeletal muscle.
Indexed as
Identifiers
25074283What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.