ArticleAmerican journal of epidemiology2014
Maternal genitourinary infections and the risk of gastroschisis.
Article in American journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Medication use during pregnancy and the risk of gastroschisis: a systematic review and meta-analysis of observational studies.Orphanet journal of rare diseases · 2024Pooled it
- Public health priorities for gastroschisis: Summary of a meeting sponsored by the Centers for Disease Control and Prevention and the March of Dimes.Birth defects research · 2024Article
- Maternal periconceptional alcohol consumption and gastroschisis in the National Birth Defects Prevention Study, 1997-2011.Paediatric and perinatal epidemiology · 2022Article
- Maternal occupational exposure to solvents and gastroschisis in offspring - National Birth Defects Prevention Study 1997-2011.Occupational and environmental medicine · 2020Article
- Risk of gastroschisis with maternal genitourinary infections: the US National birth defects prevention study 1997-2011.BMJ open · 2019Article
- A machine learning approach to investigate potential risk factors for gastroschisis in California.Birth defects research · 2019Article
- Maternal genitourinary infections and risk of birth defects in the National Birth Defects Prevention Study.Birth defects research · 2018Article
- Complexity of gastroschisis predicts outcome: epidemiology and experience in an Australian tertiary centre.BMC pregnancy and childbirth · 2018Article
- Possible etiologies of increased incidence of gastroschisis.Pediatric surgery international · 2017Article
- Maternal Antibodies to Chlamydia trachomatis and Risk of Gastroschisis.Birth defects research · 2017Article
- Maternal Antibodies to Herpes Virus Antigens and Risk of Gastroschisis in Offspring.American journal of epidemiology · 2016Article
- Chlamydia trachomatis IgG3 seropositivity is associated with gastroschisis.Journal of perinatology : official journal of the California Perinatal Association · 2015Article
- Adjusting for bias due to incomplete case ascertainment in case-control studies of birth defects.American journal of epidemiology · 2015Article
- New clues to understand gastroschisis. Embryology, pathogenesis and epidemiology.Colombia medica (Cali, Colombia)Review
- Does meconium contaminated amniotic fluid affect intestinal wall thickness and functional outcome in patients with anterior abdominal wall defects?African journal of paediatric surgery : AJPSObservational
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Genitourinary infections (GUIs) have been associated with increased risk of gastroschisis in 2 studies. Using data collected in the Slone Epidemiology Center Birth Defects Study, we examined the association between GUI and gastroschisis. From 1998 to 2010, mothers of 249 gastroschisis cases and 7,104 controls were interviewed within 6 months of delivery about pregnancy events, including vaginal infections, genital herpes, urinary tract infections (UTIs), and other sexually transmitted diseases (STDs). Women were considered exposed if they reported at least 1 instance of a GUI in the first trimester. Logistic regression models were used to calculate odds ratios and 95% confidence intervals. Women who reported having any GUI had an adjusted odds ratio of 1.8 (95% confidence interval (CI): 1.3, 2.4). The highest risk was seen among women who reported a UTI only (adjusted odds ratio = 2.3, 95% CI: 1.5, 3.5), while the odds ratio for an STD only was slightly elevated (adjusted odds ratio = 1.2, 95% CI: 1.0, 1.5). Among women under 25 years of age, the odds ratio for UTI only was 2.6 (95% CI: 1.7, 4.0), and among older women it was 1.8 (95% CI: 0.6, 5.9). When we considered the joint association of UTIs and young maternal age, a synergistic effect was observed. The results of this study add further evidence that UTIs may increase the risk of gastroschisis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.