ArticleJournal of the American Chemical Society2014
Proton-induced reactivity of NO⁻ from a {CoNO}⁸ complex.
Article in Journal of the American Chemical Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Article
- Tandem Synthesis of N,O-Containing Heterocycles via Nitrite Upcycling at a Trifunctional Cobalt Catalyst.Journal of the American Chemical Society · 2025Article
- Developing Photoactive Coumarin-CagedMolecules (Basel, Switzerland) · 2024Article
- Spectroscopic and Computational pH Study of NiMolecules (Basel, Switzerland) · 2023Article
- Unraveling Metal-Ligand Bonding in an HNO-Evolving {FeNO}Journal of the American Chemical Society · 2023Article
- Azanone (HNO): generation, stabilization and detection.Chemical science · 2021Review
- The role of porphyrin peripheral substituents in determining the reactivities of ferrous nitrosyl species.Chemical science · 2020Article
- Bioinspired oxidation of oximes to nitric oxide with dioxygen by a nonheme iron(II) complex.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020Article
- A Mononuclear, Nonheme FeJournal of the American Chemical Society · 2019Article
- Extension of C. elegans lifespan using the ·NO-delivery dinitrosyl iron complexes.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2018Article
- Recent advances in the chemical biology of nitroxyl (HNO) detection and generation.Nitric oxide : biology and chemistry · 2016Review
- Fine-tuning of Substrate Affinity Leads to Alternative Roles of Mycobacterium tuberculosis Fe2+-ATPases.The Journal of biological chemistry · 2016Article
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Authors and funding
6 authors.
Funding
Abstract
Research on the one-electron reduced analogue of NO, namely nitroxyl (HNO/NO(-)), has revealed distinguishing properties regarding its utility as a therapeutic. However, the fleeting nature of HNO requires the design of donor molecules. Metal nitrosyl (MNO) complexes could serve as potential HNO donors. The synthesis, spectroscopic/structural characterization, and HNO donor properties of a {CoNO}(8) complex in a pyrrole/imine ligand frame are reported. The {CoNO}(8) complex [Co(LN4(PhCl))(NO)] (1) does not react with established HNO targets such as Fe(III) hemes or Ph3P. However, in the presence of stoichiometric H(+) 1 behaves as an HNO donor. Complex 1 readily reacts with [Fe(TPP)Cl] or Ph3P to afford the {FeNO}(7) porphyrin or Ph3P═O/Ph3P═NH, respectively. In the absence of an HNO target, the {Co(NO)2}(10) dinitrosyl (3) is the end product. Complex 1 also reacts with O2 to yield the corresponding Co(III)-η(1)-ONO2 (2) nitrato analogue. This report is the first to suggest an HNO donor role for {CoNO}(8) with biotargets such as Fe(III)-porphyrins.
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