Evidence map›Paper›PMID 25072821›Full record

ArticleJournal of toxicology and environmental health. Part A2014

Lead levels in the breast milk of nursing andean mothers living in a lead-contaminated environment.

S Allen Counter, Leo H Buchanan, Fernando Ortega, Roberto Chiriboga, Rommy Correa, María Angela Collaguaso

Abstract read
In one paragraph

Article in Journal of toxicology and environmental health. Part A, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S Allen Countera Department of Neurology , Harvard Medical School/The Biological Laboratories , Cambridge , Massachusetts , USA.
Leo H Buchanan
Fernando Ortega
Roberto Chiriboga
Rommy Correa
María Angela Collaguaso

Funding

TISSUE CULTURE CORE FACILITYP30HD004147 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MCILVANE, WILLIAM J · 1985 to 2014
$9.1M
NICHD NIH HHS P30 HD004147
6 · The paper itself

Abstract

Concentrations of lead (Pb) in breast milk (PbM) and blood (PbB) were measured in a current cohort of lactating mothers living in Andean communities where women of childbearing age engage in the occupational use of Pb, and compared to results obtained in earlier studies. Mean PbM concentration in the current group of breastfeeding mothers tested in 2012/2013 was 3.73 μg/L (SD: 7.3; range: 0.049-28.04), and significantly lower than the 9.83 μg/L (SD: 12.75; range: 0.2-49) previously observed in breastfeeding mothers in the study area from 1999 to 2007. Breastfeeding women in the current cohort showed an average PbM/PbB ratio of 3.6%, which is in agreement with other studies. The mean PbB level obtained for the current cohort was 7.8 μg/dl (SD: 5.2; range: 1.4-21), and significantly lower than the mean PbB level of 20.8 μg/dl (SD: 16.4; range: 4-73) obtained for the comparison group of breastfeeding mothers tested between 1999 and 2007. A correlation of .687 between paired PbM and maternal PbB was found, indicating that maternal PbB level is a significant predictor of PbM. Current PbM levels remain higher than international averages, but indicate that maternal Pb exposure has declined over time in the environmentally Pb-contaminated study area. The current reduction in Pb in milk and blood of breastfeeding mothers may be due to adherence to a Pb-exposure education and prevention program initiated by the authors in the study area years earlier, as well as recent improvements in local health care delivery.

Indexed as

AdolescentAdultArsenicCadmiumCohort StudiesEcuadorEnvironmental ExposureFemaleHumansLactationLeadMercuryMilk, HumanMothersProtoporphyrinsYoung AdultArsenicCadmiumLeadMercuryProtoporphyrinszinc protoporphyrin

Identifiers

PMID25072821
PMCPMC4373535

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.