Evidence map›Paper›PMID 25072608›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2014

Process monitoring of an HIV treatment as prevention program in British Columbia, Canada.

Lillian Lourenço, Viviane D Lima, Kate Heath, Bohdan Nosyk, Mark Gilbert, Guillaume Colley, Theodora Consolacion, Rolando Barrios, Robert Hogg, Mel Krajden and 11 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Observational
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  15. Sexual and reproductive health and human rights of women living with HIV.Journal of the International AIDS Society · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 10 institutions in 2 countries.

Lillian Lourenço*British Columbia Centre for Excellence in HIV/AIDS, Providence Health Care, Vancouver, Canada; †Division of AIDS, Department of Medicine, University of British Columbia, Vancouver, Canada; ‡Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada; §British Columbia Centre for Disease Control, Vancouver, Canada; ‖Vancouver Coastal Health Authority, Vancouver, Canada; ¶Fraser Health Authority, Surrey, Canada; #First Nations Health Authority, West Vancouver, Canada; **Interior Health Authority, Kelowna, Canada; ††Northern Health Authority, Prince George, Canada; ‡‡Oak Tree Clinic, Provincial Health Services Authority, Vancouver, Canada; and §§Vancouver Island Health Authority, Victoria, Canada.
Viviane D Lima
Kate Heath
Bohdan Nosyk
Mark Gilbert
Guillaume Colley
Theodora Consolacion
Rolando Barrios
Robert Hogg
Mel Krajden
Stephanie Konrad
Michelle Murti
Joanne Nelson
Jennifer May-Hadford
James Haggerstone
Neora Pick
Reka Gustafson
Melanie Rusch
Irene Day
Julio S G Montaner
STOP HIV/AIDS Study Group
AIDS Vancouver · CABC Centre for Disease Control · CAProvidence Health Care · CAFraser Health · CAVancouver Coastal Health · CAInterior Health · CAIsland Health · CANorthern Health · AUProvincial Health Services Authority · CAUniversity of British Columbia · CA

Funding

Seek and Treat for Optimal Outcomes and Prevention in HIV & AIDS in IDUDP1DA026182 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MONTANER, JULIO SERGIO GONZALEZ · 2008 to 2013
$3.9M
Seek and Treat for Optimal Prevention of HIV & AIDS (STOP HIV/AIDS) in BCR01DA036307 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MONTANER, JULIO SERGIO GONZALEZ · 2013 to 2017
$3.0M
STOP HIV in DUsR01DA031043 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI HULL, MARK, MONTANER, JULIO SERGIO GONZALEZ · 2011 to 2016
$2.2M
Modeling different strategies to reduce the public health impact of the HCV/HIV eR03DA033851 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI LIMA, VIVIANE DIAS · 2012 to 2013
$55k
CIHR 125948-1CIHR 129971-1CIHR MOP-125948NIDA NIH HHS 1DP1DA026182NIDA NIH HHS DP1 DA026182NIDA NIH HHS R01 DA031043NIDA NIH HHS R01 DA036307NIDA NIH HHS R01DA036307NIDA NIH HHS R03 DA033851NIDA NIH HHS R03DA033851-01
6 · The paper itself

Abstract

backgroundIn light of accumulated scientific evidence of the secondary preventive benefits of antiretroviral therapy, a growing number of jurisdictions worldwide have formally started to implement HIV Treatment as Prevention (TasP) programs. To date, no gold standard for TasP program monitoring has been described. Here, we describe the design and methods applied to TasP program process monitoring in British Columbia (BC), Canada.

methodsMonitoring indicators were selected through a collaborative and iterative process by an interdisciplinary team including representatives from all 5 regional health authorities, the BC Centre for Disease Control (BCCDC), and the BC Centre for Excellence in HIV/AIDS (BC-CfE). An initial set of 36 proposed indicators were considered for inclusion. These were ranked on the basis of 8 criteria: data quality, validity, scientific evidence, informative power of the indicator, feasibility, confidentiality, accuracy, and administrative requirement. The consolidated list of indicators was included in the final monitoring report, which was executed using linked population-level data.

resultsA total of 13 monitoring indicators were included in the BC TasP Monitoring Report. Where appropriate, indicators were stratified by subgroups of interest, including HIV risk group and demographic characteristics. Six Monitoring Reports are generated quarterly: 1 for each of the regional health authorities and a consolidated provincial report.

conclusionsWe have developed a comprehensive TasP process monitoring strategy using evidence-based HIV indicators derived from linked population-level data. Standardized longitudinal monitoring of TasP program initiatives is essential to optimize individual and public health outcomes and to enhance program efficiencies.

Indexed as

Antiretroviral Therapy, Highly ActiveBritish ColumbiaCD4 Lymphocyte CountEvidence-Based MedicineHIV InfectionsHumansProgram EvaluationQuality Indicators, Health CareViral Load

Identifiers

PMID25072608
PMCPMC4257704
OpenAlexW2330015203

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.