ArticleThe ISME journal2015
Exploring functional contexts of symbiotic sustain within lichen-associated bacteria by comparative omics.
Article in The ISME journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
108 citing papers in PubMed, 1 synthesis or guideline pooled it, 274 citations in OpenAlex.
- A review of the potential of lichen substances as antifungal agents: the effects of extracts and lichen secondary metabolites on Fusarium fungi.Archives of microbiology · 2022Pooled it
- Factors shaping the lichen photobiome and mycobiome in a tropical lichen community.FEMS microbiology ecology · 2026Article
- The Impact of Visible Symptoms of Thallus Damage on the Phycobiota of Mediterranean Epiphytic Lichens.Microbial ecology · 2026Article
- Fog, Symbiosis, and Survival: The Ecological Architecture of the Grit Crust From the Atacama Desert Represents a Lichen Holobiome Rather Than a Soil Microbiome.Environmental microbiology · 2026Article
- Exploring the lichenization continuum through the marine tripartite symbiosis of Collemopsidium pelvetiae.American journal of botany · 2026Article
- Comparative genomic and physiological characterization of a lichen-associated Streptacidiphilus strain from Antarctica.Scientific reports · 2026Article
- Multivariate Chemoprospecting of Five Ethnobotanically Important Himalayan Lichens Identifies Parmotrema austrosinense as a Promising Source of Phenolic Antioxidants.Chemistry & biodiversity · 2026Article
- Functional redundancy and stability support the resilience of the Evernia prunastri holobiont under urbanization.Environmental microbiome · 2026Article
- Review
- Plant-pollinator interactions and floral and nectar traits shape the diversity of the nectar mycobiome.Scientific reports · 2026Article
- Convergent symbioses: morphology, life history, and niche specialization in coral and lichen mutualisms.FEMS microbiology reviews · 2026Review
- Article
- Unveiling the ecological processes driving soil and lichen microbiome assembly along an urbanization gradient.NPJ biofilms and microbiomes · 2025Article
- A Biosynthetic and Taxonomic Atlas of the Global Lichen Holobiont.Environmental microbiology · 2025Article
- Intrathalline Fungal and Bacterial Diversity Is Uncovered in Antarctic Lichen Symbioses.Environmental microbiology reports · 2025Article
- Elevational microhabitats influence some endolichenic traits of Umbilicaria aprina, an alpine lichen species.Scientific reports · 2025Article
- Distinct bacteria display genus and species-specific associations with mycobionts in paramo lichens in Colombia.FEMS microbiology ecology · 2025Article
- Genomic features of lichen-associated black fungi.IUBMB life · 2025Article
- Comprehensive analysis of the mitochondrial genome in lichen genusFrontiers in microbiology · 2025Article
- Microbial occurrence and symbiont detection in a global sample of lichen metagenomes.PLoS biology · 2024Article
48 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
Symbioses represent a frequent and successful lifestyle on earth and lichens are one of their classic examples. Recently, bacterial communities were identified as stable, specific and structurally integrated partners of the lichen symbiosis, but their role has remained largely elusive in comparison to the well-known functions of the fungal and algal partners. We have explored the metabolic potentials of the microbiome using the lung lichen Lobaria pulmonaria as the model. Metagenomic and proteomic data were comparatively assessed and visualized by Voronoi treemaps. The study was complemented with molecular, microscopic and physiological assays. We have found that more than 800 bacterial species have the ability to contribute multiple aspects to the symbiotic system, including essential functions such as (i) nutrient supply, especially nitrogen, phosphorous and sulfur, (ii) resistance against biotic stress factors (that is, pathogen defense), (iii) resistance against abiotic factors, (iv) support of photosynthesis by provision of vitamin B12, (v) fungal and algal growth support by provision of hormones, (vi) detoxification of metabolites, and (vii) degradation of older parts of the lichen thallus. Our findings showed the potential of lichen-associated bacteria to interact with the fungal as well as algal partner to support health, growth and fitness of their hosts. We developed a model of the symbiosis depicting the functional multi-player network of the participants, and argue that the strategy of functional diversification in lichens supports the longevity and persistence of lichens under extreme and changing ecological conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.