ReviewFrontiers in public health2014
Tick-borne pathogen - reversed and conventional discovery of disease.
Review in Frontiers in public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed.
- Deep sequencing of 16mSystems · 2025Article
- Ticks and tick-borne diseases in the northern hemisphere affecting humans.Frontiers in microbiology · 2025Review
- Article
- Molecular Detection and Characterization of Rickettsia Species in Ixodid Ticks from Selected Regions of Namibia.Microorganisms · 2024Article
- The Eruptive Fevers at Sixes and Sevens.Open access emergency medicine : OAEM · 2024Article
- Virome diversity of ticks feeding on domestic mammals in China.Virologica Sinica · 2023Article
- Bacteria related to tick-borne pathogen assemblages in Ornithodoros cf. hasei (Acari: Argasidae) and blood of the wild mammal hosts in the Orinoquia region, Colombia.Experimental & applied acarology · 2022Article
- Self-reported symptoms and health complaints associated with exposure to Ixodes ricinus-borne pathogens.Parasites & vectors · 2022Article
- No molecular detection of tick-borne pathogens in the blood of patients with erythema migrans in Belgium.Parasites & vectors · 2022Article
- Virome analysis of ticks in a forest region of Liaoning, China: characterization of a novel hepe-like virus sequence.Virology journal · 2021Article
- Tick and Tickborne Pathogen Surveillance as a Public Health Tool in the United States.Journal of medical entomology · 2021Review
- Review
- Reported County-Level Distribution of Lyme Disease Spirochetes, Borrelia burgdorferi sensu stricto and Borrelia mayonii (Spirochaetales: Spirochaetaceae), in Host-Seeking Ixodes scapularis and Ixodes pacificus Ticks (Acari: Ixodidae) in the Contiguous United States.Journal of medical entomology · 2021Article
- Circulation ofPathogens (Basel, Switzerland) · 2021Article
- Red and fallow deer determine the density of Ixodes ricinus nymphs containing Anaplasma phagocytophilum.Parasites & vectors · 2021Article
- Induced Transient Immune Tolerance in Ticks and Vertebrate Host: A Keystone of Tick-Borne Diseases?Frontiers in immunology · 2021Review
- Evaluation of a novel multiplex PCR amplicon sequencing assay for detection of human pathogens in Ixodes ticks.Ticks and tick-borne diseases · 2020Article
- Evaluation of Disease Causality of RarePathogens (Basel, Switzerland) · 2020Review
- Impact of vertebrate communities on Ixodes ricinus-borne disease risk in forest areas.Parasites & vectors · 2019Article
- Detection of pathogens inHeliyon · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular methods have increased the number of known microorganisms associated with ticks significantly. Some of these newly identified microorganisms are readily linked to human disease while others are yet unknown to cause human disease. The face of tick-borne disease discovery has changed with more diseases now being discovered in a "reversed way," detecting disease cases only years after the tick-borne microorganism was first discovered. Compared to the conventional discovery of infectious diseases, reverse order discovery presents researchers with new challenges. Estimating public health risks of such agents is especially challenging, as case definitions and diagnostic procedures may initially be missing. We discuss the advantages and shortcomings of molecular methods, serology, and epidemiological studies that might be used to study some fundamental questions regarding newly identified tick-borne diseases. With increased tick-exposure and improved detection methods, more tick-borne microorganisms will be added to the list of pathogens causing disease in humans in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.