ArticleBiomedical optics express2014
Optimization of camera exposure durations for multi-exposure speckle imaging of the microcirculation.
Article in Biomedical optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Comparing multi- and single-exposure speckle contrast optical spectroscopy methods as estimators of blood flow in the diffuse regime.Journal of biomedical optics · 2026Article
- Wide-field intensity fluctuation imaging.Biomedical optics express · 2024Article
- Mechanoreceptor sensory feedback is impaired by pressure induced cutaneous ischemia on the human foot sole and can predict cutaneous microvascular reactivity.Frontiers in neuroscience · 2024Article
- Quasi-analytic solution for real-time multi-exposure speckle imaging of tissue perfusion.Biomedical optics express · 2023Article
- Wide-field Intensity Fluctuation Imaging.bioRxiv : the preprint server for biology · 2023Article
- A quasi-analytic solution for real-time multi-exposure speckle imaging of tissue perfusion.bioRxiv : the preprint server for biology · 2023Article
- All fiber-based illumination system for multi-exposure speckle imaging.Biomedical optics express · 2023Article
- Synthetic exposure with a CMOS camera for multiple exposure speckle imaging of blood flow.Scientific reports · 2022Article
- Dynamics of isoflurane-induced vasodilation and blood flow of cerebral vasculature revealed by multi-exposure speckle imaging.Journal of neuroscience methods · 2022Article
- Robust quantitative single-exposure laser speckle imaging with true flow speckle contrast in the temporal and spatial domains.Biomedical optics express · 2019Article
- Multiple speckle exposure imaging for the study of blood flow changes induced by functional activation of barrel cortex and olfactory bulb in mice.Neurophotonics · 2019Article
- Simultaneously extracting multiple parameters via multi-distance and multi-exposure diffuse speckle contrast analysis.Biomedical optics express · 2017Article
- Intraoperative multi-exposure speckle imaging of cerebral blood flow.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2017Article
- Sensitivity of laser speckle contrast imaging to flow perturbations in the cortex.Biomedical optics express · 2016Article
- High-speed multi-exposure laser speckle contrast imaging with a single-photon counting camera.Biomedical optics express · 2015Article
- Expanding applications, accuracy, and interpretation of laser speckle contrast imaging of cerebral blood flow.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2015Review
- Flux or speed? Examining speckle contrast imaging of vascular flows.Biomedical optics express · 2015Article
- Accessing to arteriovenous blood flow dynamics response using combined laser speckle contrast imaging and skin optical clearing.Biomedical optics express · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Improved Laser Speckle Contrast Imaging (LSCI) blood flow analyses that incorporate inverse models of the underlying laser-tissue interaction have been used to develop more quantitative implementations of speckle flowmetry such as Multi-Exposure Speckle Imaging (MESI). In this paper, we determine the optimal camera exposure durations required for obtaining flow information with comparable accuracy with the prevailing MESI implementation utilized in recent in vivo rodent studies. A looping leave-one-out (LOO) algorithm was used to identify exposure subsets which were analyzed for accuracy against flows obtained from analysis with the original full exposure set over 9 animals comprising n = 314 regional flow measurements. From the 15 original exposures, 6 exposures were found using the LOO process to provide comparable accuracy, defined as being no more than 10% deviant, with the original flow measurements. The optimal subset of exposures provides a basis set of camera durations for speckle flowmetry studies of the microcirculation and confers a two-fold faster acquisition rate and a 28% reduction in processing time without sacrificing accuracy. Additionally, the optimization process can be used to identify further reductions in the exposure subsets for tailoring imaging over less expansive flow distributions to enable even faster imaging.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.