ArticleIranian journal of reproductive medicine2014
Protective effect of Urtica dioica L against nicotine-induced damage on sperm parameters, testosterone and testis tissue in mice.
Article in Iranian journal of reproductive medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Article
- Article
- The Aphrodisiac and Androgenic Effects of Aqueous and Ethanol Extracts ofTheScientificWorldJournal · 2025Article
- Review
- Article
- Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.Psychopharmacology · 2023Article
- Paternal alcohol consumption has intergenerational consequences in male offspring.Journal of assisted reproduction and genetics · 2022Article
- Combined Effects of Exercise and Phytoanabolic Extracts in Castrated Male and Female Mice.Nutrients · 2021Article
- Nicotine-induced oxidative stress, testis injury, AChE inhibition and brain damage alleviated by Mentha spicata.Inflammopharmacology · 2020Article
- Ameliorative Effect of Melatonin Against Reproductive Toxicity of Tramadol in Rats via the Regulation of Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis-related Gene Expression Signaling Pathway.Addiction & health · 2020Article
- Effect of Thymoquinone on Reproductive Parameter in Morphine-treated Male Mice.Advanced biomedical research · 2018Article
- The Effects of Thymoquinone Against Morphine-induced Damages on Male Mice Liver.International journal of preventive medicine · 2018Article
- Investigating Chemical Composition and Indications of Hydrosol Soft Drinks (Aromatic Waters) Used in Persian Folk Medicine for Women's Hormonal and Reproductive Health Conditions.Journal of evidence-based complementary & alternative medicine · 2017Article
- Use of lipid-lowering medicinal herbs during pregnancy: A systematic review on safety and dosage.ARYA atherosclerosis · 2017Review
- Expression Changes of Apoptotic Genes in Tissues from Mice Exposed to NicotineAsian Pacific journal of cancer prevention : APJCP · 2017Article
- Curcumin improves liver damage in male mice exposed to nicotine.Journal of traditional and complementary medicine · 2016Article
- Etiologies of sperm oxidative stress.International journal of reproductive biomedicine · 2016Review
- Effect of Genistein on reproductive parameter and serum nitric oxide levels in morphine-treated mice.International journal of reproductive biomedicine · 2016Article
- Crocin Improves Damage Induced by Nicotine on A Number of Reproductive Parameters in Male Mice.International journal of fertility & sterilityArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNicotine consumption can decrease fertility drive in males by inducing oxidative stress and DNA damage. Urtica dioica L (U.dioica) is a multipurpose herb in traditional medicine for which some anti-oxidative and anti-inflammatory properties have been identified.
objectiveThe main goal is to investigate whether the U.dioica could inhibit nicotine adverse effects on sperm cells viability, count, motility, and testis histology and testosterone hormone. MATERIALS AND
methodsIn this study, hydro-alcoholic extract of U.dioica was prepared and various doses of U.dioica (0, 10, 20, and 50 mg/kg) and U.dioica plus nicotine (0, 10, 20, and 50 mg/kg) were administered intraperitoneally to 56 male mice for 28 consequent days. These mice were randomly assigned to 8 groups (n=7) and sperm parameters (sperm cells viability, count, motility, and morphology), testis and prostate weight, testis histology and testosterone hormone were analyzed and compared.
resultsThe results indicated that nicotine administration (0.5 mg/kg) significantly decreased testosterone level, count and motility of sperm cells, and testis weight compared to control group (p=0.00). However, increasing the dose of U.dioica significantly boosted motility, count, normal morphology of sperm cells, seminiferous tubules diameter, and testosterone in all groups compared to control (p=0.00) and testis weight in 20 and 50 mg/kg doses in comparison with control group (p=0.00).
conclusionIt seems that U.dioica hydro-alcoholic extract administration could increase the quality of spermatozoa and inhibits nicotine-induced adverse effects on sperm parameters.
Indexed as
Identifiers
25071848PMC4111888What OpenQuestion holds
Registered trials
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