ReviewFrontiers in genetics2014
The Missing lnc(RNA) between the pancreatic β-cell and diabetes.
Review in Frontiers in genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 48 citations in OpenAlex.
- Review
- Vitamin D ameliorated endothelial cell damage induced by diabetes via regulation of lncRNA MEG3 in human umbilical vein endothelial cells.Archives of medical science : AMS · 2026Article
- LncRNA NBR2 affects pancreatic β-cell function in type 2 diabetes mellitus by targeting miR-646.Diabetology & metabolic syndrome · 2025Article
- The transcript level of long non-coding RNAs; MALAT1 and TUG1, and the association with metabolic syndrome-related parameters in women with overweight and obesity.Journal of diabetes and metabolic disorders · 2024Article
- LncSTPred: a predictive model of lncRNA subcellular localization and decipherment of the biological determinants influencing localization.Frontiers in molecular biosciences · 2024Article
- The role of long non-coding RNAs in the development of adipose cells.Non-coding RNA research · 2023Review
- Circulating microRNAs Suggest Networks Associated with Biological Functions in Aggressive Refractory Type 2 Celiac Disease.Biomedicines · 2022Article
- Long non-coding RNA HCG18 promotes gastric cancer progression by regulating miRNA-146a-5p/tumor necrosis factor receptor-associated factor 6 axis.Bioengineered · 2022Article
- The long non-coding RNA βFaar regulates islet β-cell function and survival during obesity in mice.Nature communications · 2021Article
- Long Non-coding RNA 332443 Inhibits Preadipocyte Differentiation by Targeting Runx1 and p38-MAPK and ERK1/2-MAPK Signaling Pathways.Frontiers in cell and developmental biology · 2021Article
- The long non-coding RNA Meg3 is dispensable for hematopoietic stem cells.Scientific reports · 2019Article
- Long noncoding RNA MALAT1 acts as a competing endogenous RNA to regulate Amadori-glycated albumin-induced MCP-1 expression in retinal microglia by a microRNA-124-dependent mechanism.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2018Article
- DNA methylation of imprinted genes in Mexican-American newborn children with prenatal phthalate exposure.Epigenomics · 2018Article
- The Cells of the Islets of Langerhans.Journal of clinical medicine · 2018Review
- Inhibition of E-cadherin expression by lnc-RNA H19 to facilitate bladder cancer metastasis.Cancer biomarkers : section A of Disease markers · 2018Article
- Role of DNA methylation in imprinting disorders: an updated review.Journal of assisted reproduction and genetics · 2017Review
- Therapeutic Approaches and Role of ncRNAs in Cardiovascular Disorders and Insulin Resistance.BioMed research international · 2017Review
- Long noncoding RNA variations in cardiometabolic diseases.Journal of human genetics · 2017Review
- Environmental Health and Long Non-coding RNAs.Current environmental health reports · 2016Review
- Progress and prospects of long noncoding RNAs in lipid homeostasis.Molecular metabolism · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Diabetes mellitus represents a group of complex metabolic diseases that result in impaired glucose homeostasis, which includes destruction of β-cells or the failure of these insulin-secreting cells to compensate for increased metabolic demand. Despite a strong interest in characterizing the transcriptome of the different human islet cell types to understand the molecular basis of diabetes, very little attention has been paid to the role of long non-coding RNAs (lncRNAs) and their contribution to this disease. Here we summarize the growing evidence for the potential role of these lncRNAs in β-cell function and dysregulation in diabetes, with a focus on imprinted genomic loci.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.