ReviewFrontiers in immunology2014
Every breath you take: the impact of environment on resident memory CD8 T cells in the lung.
Review in Frontiers in immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Article
- Increased cytotoxic T-cells in the airways of adults with former bronchopulmonary dysplasia.The European respiratory journal · 2022Article
- Differential Immune Response Following Intranasal and Intradermal Infection withMicroorganisms · 2021Review
- Immunophenotyping of Rhesus CMV-Specific CD8 T-Cell Populations.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2021Article
- Influenza-Specific Lung-Resident Memory CD8Cold Spring Harbor perspectives in biology · 2021Review
- Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8ACS nano · 2019Article
- Improving the Quality and Reproducibility of Flow Cytometry in the Lung. An Official American Thoracic Society Workshop Report.American journal of respiratory cell and molecular biology · 2019Article
- TRAV1-2Communications biology · 2019Article
- The Respiratory Environment Diverts the Development of Antiviral Memory CD8 T Cells.Journal of immunology (Baltimore, Md. : 1950) · 2018Article
- CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin.Journal of immunology (Baltimore, Md. : 1950) · 2018Article
- Polyanhydride Nanovaccine Induces Robust Pulmonary B and T Cell Immunity and Confers Protection Against Homologous and Heterologous Influenza A Virus Infections.Frontiers in immunology · 2018Article
- Incomplete Memories: The Natural Suppression of Tissue-Resident Memory CD8 T Cells in the Lung.Frontiers in immunology · 2018Article
- CD8Frontiers in immunology · 2018Review
- Memory Inflation Drives Tissue-Resident Memory CD8Frontiers in immunology · 2018Article
- Plasmacytoid Dendritic Cells Contribute to the Protective Immunity Induced by Intranasal Treatment with Fc-fused Interleukin-7 against Lethal Influenza Virus Infection.Immune network · 2017Article
- Article
- Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T cells in the lung.Mucosal immunology · 2017Article
- An altered endometrial CD8 tissue resident memory T cell population in recurrent miscarriage.Scientific reports · 2017Article
- Original Antigenic Sin Response to RNA Viruses and Antiviral Immunity.Immune network · 2016Review
- Intranasal Vaccination Affords Localization and Persistence of Antigen-Specific CD8⁺ T Lymphocytes in the Female Reproductive Tract.Vaccines · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Resident memory T cells (TRM) are broadly defined as a population of T cells, which persist in non-lymphoid sites long-term, do not re-enter the circulation, and are distinct from central memory T cells (TCM) and circulating effector memory T cells (TEM). Recent studies have described populations of TRM cells in the skin, gut, lungs, and nervous tissue. However, it is becoming increasingly clear that the specific environment in which the TRM reside can further refine their phenotypical and functional properties. Here, we focus on the TRM cells that develop following respiratory infection and reside in the lungs and the lung airways. Specifically, we will review recent studies that have described some of the requirements for establishment of TRM cells in these tissues, and the defining characteristics of TRM in the lungs and lung airways. With continual bombardment of the respiratory tract by both pathogenic and environmental antigens, dynamic fluctuations in the local milieu including homeostatic resources and niche restrictions can impact TRM longevity. Beyond a comprehensive characterization of lung TRM cells, special attention will be placed on studies, which have defined how the microenvironment of the lung influences memory T cell survival at this site. As memory T cell populations in the lung airways are requisite for protection yet wane numerically over time, developing a comprehensive picture of factors which may influence TRM development and persistence at these sites is important for improving T cell-based vaccine design.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.