ArticleFrontiers in microbiology2014
The filamentous phage XacF1 causes loss of virulence in Xanthomonas axonopodis pv. citri, the causative agent of citrus canker disease.
Article in Frontiers in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed, 62 citations in OpenAlex.
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- The potential of bacteriocins and bacteriophages to control bacterial disease of crops with a focus onJournal of the Royal Society of New Zealand · 2025Review
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- First Characterization ofViruses · 2024Article
- The role of rhizosphere phages in soil health.FEMS microbiology ecology · 2024Review
- Characterization of a Filamentous Phage, Vaf1, fromApplied and environmental microbiology · 2023Article
- Citrus Canker Pathogen, Its Mechanism of Infection, Eradication, and Impacts.Plants (Basel, Switzerland) · 2022Review
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- Xanthomonas bacteriophages: a review of their biology and biocontrol applications in agriculture.BMC microbiology · 2021Review
- Bacteriophage-Mediated Control of Phytopathogenic Xanthomonads: A Promising Green Solution for the Future.Microorganisms · 2021Review
- First Report of Filamentous Phages Isolated from Tunisian Orchards to ControlMicroorganisms · 2020Article
- Beyond Cholera: Characterization ofViruses · 2020Article
- Bacteriophage Usage for Bacterial Disease Management and Diagnosis in Plants.The plant pathology journal · 2020Review
- Biosynthesis of silver nanoparticles using endophytic bacteria and their role in inhibition of rice pathogenic bacteria and plant growth promotion.RSC advances · 2019Article
- Filamentous phages: masters of a microbial sharing economy.EMBO reports · 2019Review
- Application of filamentous phages in environment: A tectonic shift in the science and practice of ecorestoration.Ecology and evolution · 2019Article
- Excisionase in Pf filamentous prophage controls lysis-lysogeny decision-making in Pseudomonas aeruginosa.Molecular microbiology · 2019Article
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, filamentous phage XacF1, which can infect Xanthomonas axonopodis pv. citri (Xac) strains, was isolated and characterized. Electron microscopy showed that XacF1 is a member of the family Inoviridae and is about 600 nm long. The genome of XacF1 is 7325 nucleotides in size, containing 13 predicted open reading frames (ORFs), some of which showed significant homology to Ff-like phage proteins such as ORF1 (pII), ORF2 (pV), ORF6 (pIII), and ORF8 (pVI). XacF1 showed a relatively wide host range, infecting seven out of 11 strains tested in this study. Frequently, XacF1 was found to be integrated into the genome of Xac strains. This integration occurred at the host dif site (attB) and was mediated by the host XerC/D recombination system. The attP sequence was identical to that of Xanthomonas phage Cf1c. Interestingly, infection by XacF1 phage caused several physiological changes to the bacterial host cells, including lower levels of extracellular polysaccharide production, reduced motility, slower growth rate, and a dramatic reduction in virulence. In particular, the reduction in virulence suggested possible utilization of XacF1 as a biological control agent against citrus canker disease.
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