ArticleFrontiers in neurology2014
Sleep disturbances and autonomic dysfunction in patients with postural orthostatic tachycardia syndrome.
Article in Frontiers in neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Heart rate and heart rate variability comparison between postural orthostatic tachycardia syndrome versus healthy participants; a systematic review and meta-analysis.BMC cardiovascular disorders · 2019Pooled it
- The role of 24-hour wearable sensors in early evaluation of adolescent orthostatic dysregulation.PCN reports : psychiatry and clinical neurosciences · 2025Article
- Narcolepsy: Beyond the Classic Pentad.CNS drugs · 2025Review
- The relationship between cardiovagal baroreflex and cerebral autoregulation in postural orthostatic tachycardia disorder using advanced cross-correlation function.Scientific reports · 2024Article
- Autonomic dysfunction in idiopathic hypersomnia: an overlooked association and potential management.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Review
- Brain fog in neuropathic postural tachycardia syndrome may be associated with autonomic hyperarousal and improves after water drinking.Frontiers in neuroscience · 2022Article
- Deterioration of Sleep Quality According to Glycemic Status.Diabetes & metabolism journal · 2020Article
- Early Development of Bidirectional Associations between Sleep Disturbance and Diabetes.Diabetes & metabolism journal · 2020Article
- Heart Rate Variability in Head-Up Tilt Tests in Adolescent Postural Tachycardia Syndrome Patients.Frontiers in neuroscience · 2020Article
- Heart Rate Variability Predicts Therapeutic Response to Metoprolol in Children With Postural Tachycardia Syndrome.Frontiers in neuroscience · 2019Article
- Cognitive and psychological issues in postural tachycardia syndrome.Autonomic neuroscience : basic & clinical · 2018Review
- Health-related quality of life and suicide risk in postural tachycardia syndrome.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2017Article
- Pediatric sleep and autonomic complaints.SAGE open medicine · 2017Article
- Unexplored relationship of sleep disturbances linked to suicidal ideation and behavior in postural orthostatic tachycardia syndrome.Nature and science of sleep · 2017Article
- Sleep disturbance linked to suicidal ideation in postural orthostatic tachycardia syndrome.Nature and science of sleep · 2017Article
- Objective Sleep Assessments in Patients with Postural Tachycardia Syndrome using Overnight Polysomnograms.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2016Article
- Sleep disorders in patients with postural tachycardia syndrome.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many patients with postural tachycardia syndrome (PoTS) suffer from fatigue, daytime sleepiness, and sleeping disturbances. The objective of this study was to compare subjective and objective sleep quality of PoTS patients with a group of healthy controls. All patients completed a Pittsburgh Sleep Quality Index questionnaire and the Epworth Sleepiness Scale. The patients sleep architecture, heart rate, and heart rate variability (HRV) measurements were taken during one night at the sleep laboratorium. All data was collected at the Sleep Unit, at Helios Klinikum Wuppertal. Thirty-eight patients diagnosed with PoTS were compared to 31 healthy controls, matched in age and gender. Patients with PoTS reached significantly higher scores in sleep questionnaires, which means that they were more sleepy and had a lower sleep quality. Polysomnography showed a significantly higher proportion of stage 2 sleep. The results of HRV analysis in different sleep stages confirmed changes in autonomic activity in both groups. PoTS patients, however, showed a diminished variability of the low-frequency (LF) band, high-frequency (HF) band, and LF/HF ratio in different sleep stages. It can therefore be gathered that PoTS could be considered as potential differential diagnosis for sleep disturbances since PoTS patients had a subjective diminished sleep quality, reached higher levels of daytime sleepiness, and showed a higher proportion of stage 2 sleep. PoTS patients showed furthermore a reduction of LF/HF ratio variability in different sleep stages.
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