Evidence map›Paper›PMID 25071404›Full record

ArticleGenetics and molecular biology2014

Genomic variation and population structure detected by single nucleotide polymorphism arrays in Corriedale, Merino and Creole sheep.

Andrés N Grasso, Virginia Goldberg, Elly A Navajas, Wanda Iriarte, Diego Gimeno, Ignacio Aguilar, Juan F Medrano, Gonzalo Rincón, Gabriel Ciappesoni

Abstract read
In one paragraph

Article in Genetics and molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

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12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  3. Comparative genome-wide analysis ofFrontiers in genetics · 2025
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Andrés N GrassoMeat and Wool National Program , Instituto Nacional de Investigación Agropecuaria , Las Brujas, Canelones , Uruguay .
Virginia GoldbergMeat and Wool National Program , Instituto Nacional de Investigación Agropecuaria , Las Brujas, Canelones , Uruguay .
Elly A NavajasBiotechnology Unit , Instituto Nacional de Investigación Agropecuaria , Las Brujas, Canelones , Uruguay .
Wanda IriarteBiotechnology Unit , Instituto Nacional de Investigación Agropecuaria , Las Brujas, Canelones , Uruguay .
Diego GimenoDepartment of Animal Genetic Improvement , Secretariado Uruguayo de la Lana , Montevideo , Uruguay .
Ignacio AguilarMeat and Wool National Program , Instituto Nacional de Investigación Agropecuaria , Las Brujas, Canelones , Uruguay .
Juan F MedranoDepartment of Animal Science , University of California Davis , USA .
Gonzalo RincónDepartment of Animal Science , University of California Davis , USA .
Gabriel CiappesoniMeat and Wool National Program , Instituto Nacional de Investigación Agropecuaria , Las Brujas, Canelones , Uruguay .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

the aim of this study was to investigate the genetic diversity within and among three breeds of sheepCorriedale, Merino and Creole. Sheep from the three breeds (Merino n = 110, Corriedale n = 108 and Creole n = 10) were genotyped using the Illumina Ovine SNP50 beadchip(®). Genetic diversity was evaluated by comparing the minor allele frequency (MAF) among breeds. Population structure and genetic differentiation were assessed using STRUCTURE software, principal component analysis (PCA) and fixation index (FST). Fixed markers (MAF = 0) that were different among breeds were identified as specific breed markers. Using a subset of 18,181 single nucleotide polymorphisms (SNPs), PCA and STUCTURE analysis were able to explain population stratification within breeds. Merino and Corriedale divergent lines showed high levels of polymorphism (89.4% and 86% of polymorphic SNPs, respectively) and moderate genetic differentiation (FST = 0.08) between them. In contrast, Creole had only 69% polymorphic SNPs and showed greater genetic differentiation from the other two breeds (FST = 0.17 for both breeds). Hence, a subset of molecular markers present in the OvineSNP50 is informative enough for breed assignment and population structure analysis of commercial and Creole breeds.

Indexed as

allele frequencies breed compositionfixation indexOvine SNP50population stratificationprincipal component analysis

Identifiers

PMID25071404
PMCPMC4094612

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.