Evidence map›Paper›PMID 25071363›Full record

ArticleWorld journal of gastroenterology2014

Neutrophil-lymphocyte ratio is useful for the prognosis of patients with hepatocellular carcinoma.

Huseyin Kayadibi, Erdim Sertoglu, Metin Uyanik, Serkan Tapan

Abstract readLetterComment
In one paragraph

Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Is neutrophil-lymphocyte ratio associated with the severity of allergic rhinitis in children?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Huseyin KayadibiHuseyin Kayadibi, Department of Medical Biochemistry, Adana Military Hospital, Adana 01150, Turkey.
Erdim SertogluHuseyin Kayadibi, Department of Medical Biochemistry, Adana Military Hospital, Adana 01150, Turkey.
Metin UyanikHuseyin Kayadibi, Department of Medical Biochemistry, Adana Military Hospital, Adana 01150, Turkey.
Serkan TapanHuseyin Kayadibi, Department of Medical Biochemistry, Adana Military Hospital, Adana 01150, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is increasing evidence that neutrophil-lymphocyte ratio (NLR) may play a role in predicting recurrence in patients with hepatitis B virus-related hepatocellular carcinoma (HCC) after liver transplantation. In the original study by Yan et al, it was aimed to determine whether an elevated NLR is associated with tumor recurrence. Total tumor size (> 9 cm) and macro-vascular invasion were found to be more significant than NLR according to the multivariate logistic regression analysis. Therefore, substantive significance should be emphasized rather than NLR because total tumor size and macro-vascular invasion are easier and more expressive than NLR in assessing HCC recurrence. NLR and platelet-lymphocyte ratio (PLR) are markers which are easy to obtain and can be used as inflammation indicators. Moreover, assessment of both NLR and PLR may add some value as a good predictor of risk for post-liver transplantation HCC recurrence. However, while the study was constructed on whole blood analysis, further details about the features and performance characteristics of the whole-blood analyzer, and preanalytical/analytical variables should also be mentioned.

Indexed as

Liver TransplantationLymphocyte CountLymphocytesNeutrophilsCarcinoma, HepatocellularFemaleHumansLiver NeoplasmsMaleHepatocellular carcinomaLiver transplantationNeutrophil-lymphocyte ratioPlatelet-to-lymphocyte ratioPrognosis

Identifiers

PMID25071363
PMCPMC4110600

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.