Evidence map›Paper›PMID 25071323›Full record

ReviewWorld journal of gastroenterology2014

Familial colorectal cancer: a review.

Franco Armelao, Giovanni de Pretis

Open access · greenAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of a Telehealth Intervention on Colonoscopy Uptake When Cost Is a Barrier: The Family CARE Cluster Randomized Controlled Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015
    Trial
  3. Optimizing genetic testing strategy for suspected attenuated adenomatous polyposis: effective solutions in public health systems.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  4. Colorectal Cancer: Risk Factors, Novel Approaches in Molecular Screening and Treatment.International journal of molecular and cellular medicine · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Colorectal Cancer Genetics: An Evolutionary Tale of Us.Clinics in colon and rectal surgery · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Frontiers in oncology · 2021
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Update on Sporadic Colorectal Cancer Genetics.Clinics in colon and rectal surgery · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Franco ArmelaoFranco Armelao, Giovanni de Pretis, Department of Gastroenterology, Ospedale Santa Chiara, Azienda Provinciale per i Servizi Sanitari, 38122 Trento, Italy.
Giovanni de PretisFranco Armelao, Giovanni de Pretis, Department of Gastroenterology, Ospedale Santa Chiara, Azienda Provinciale per i Servizi Sanitari, 38122 Trento, Italy.
Ospedale Santa Chiara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Familial colorectal cancer constitutes a heterogeneous group of patients in whom the underlying molecular mechanism is still unknown. Predisposition to a such neoplasms in this setting seems to be due to common low-penetrance genetic components, but the role of genetic testing in clinical practice has to be determined. Although screening guidelines in this moderate-risk population are empiric, data obtained in epidemiologic, meta-analyses and cohort studies and, more recently, the increased risk of advanced adenomas in first degree relatives who underwent screening colonoscopy support the need to include these individuals in specific screening programs. However, data to determine what test to use, how often to use and which organizational strategy to implement are needed. At present, screening uptake in this population is less than optimal; offering the opportunity to access to screening and improving screening uptake is a first significant step.

Indexed as

Biomarkers, TumorColorectal NeoplasmsEarly Detection of CancerGenetic Predisposition to DiseaseHeredityHumansPedigreePhenotypePredictive Value of TestsPrognosisRisk FactorsBiomarkers, TumorColorectal cancerFamilial riskHeterogeneousRisk populationScreening uptake

Identifiers

PMID25071323
PMCPMC4110560
OpenAlexW157689587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.