ArticleThe Plant cell2014
The Arabidopsis malectin-like leucine-rich repeat receptor-like kinase IOS1 associates with the pattern recognition receptors FLS2 and EFR and is critical for priming of pattern-triggered immunity.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 40 citations in OpenAlex.
- CYSTEINE-RICH RECEPTOR-LIKE KINASE5 (CRK5) and CRK22 regulate the response to Verticillium dahliae toxins.Plant physiology · 2022Article
- Authorship Issues When Articles are Retracted Due to Research Misconduct and Then Resubmitted.Science and engineering ethics · 2022Article
- FLS2-RBOHD-PIF4 Module Regulates Plant Response to Drought and Salt Stress.International journal of molecular sciences · 2022Article
- PacBio full-length transcriptome of wild apple (Malus sieversii) provides insights into canker disease dynamic response.BMC genomics · 2021Article
- Genome-wide identification and characterization of LRR-RLKs reveal functional conservation of the SIF subfamily in cotton (Gossypium hirsutum).BMC plant biology · 2018Article
- Interspecies gene transfer provides soybean resistance to a fungal pathogen.Plant biotechnology journal · 2016Article
- ERECTA and BAK1 Receptor Like Kinases Interact to Regulate Immune Responses in Arabidopsis.Frontiers in plant science · 2016Article
- Oomycete interactions with plants: infection strategies and resistance principles.Microbiology and molecular biology reviews : MMBR · 2015Review
- Enhanced Arabidopsis pattern-triggered immunity by overexpression of cysteine-rich receptor-like kinases.Frontiers in plant science · 2015Article
- Perception of pathogenic or beneficial bacteria and their evasion of host immunity: pattern recognition receptors in the frontline.Frontiers in plant science · 2015Review
- The receptor kinase IMPAIRED OOMYCETE SUSCEPTIBILITY1 attenuates abscisic acid responses in Arabidopsis.Plant physiology · 2014Article
Corrections and comments
- Retraction · 2015-05-12Concerns/Issues about Data · Concerns/Issues about Image · Manipulation of Images · Results Not Reproducible · Retract and Replace · · see republished: http://www.plantcell.org/content/28/7/1701.long
- Retracted
Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plasma membrane-localized pattern recognition receptors such as FLAGELLIN SENSING2 (FLS2) and EF-TU RECEPTOR (EFR) recognize microbe-associated molecular patterns (MAMPs) to activate the first layer of plant immunity termed pattern-triggered immunity (PTI). A reverse genetics approach with genes responsive to the priming agent β-aminobutyric acid (BABA) revealed IMPAIRED OOMYCETE SUSCEPTIBILITY1 (IOS1) as a critical PTI player. Arabidopsis thaliana ios1 mutants were hypersusceptible to Pseudomonas syringae bacteria. Accordingly, ios1 mutants demonstrated defective PTI responses, notably delayed upregulation of PTI marker genes, lower callose deposition, and mitogen-activated protein kinase activities upon bacterial infection or MAMP treatment. Moreover, Arabidopsis lines overexpressing IOS1 were more resistant to P. syringae and demonstrated a primed PTI response. In vitro pull-down, bimolecular fluorescence complementation, coimmunoprecipitation, and mass spectrometry analyses supported the existence of complexes between the membrane-localized IOS1 and FLS2 and EFR. IOS1 also associated with BRASSINOSTEROID INSENSITIVE1-ASSOCIATED KINASE1 (BAK1) in a ligand-independent manner and positively regulated FLS2/BAK1 complex formation upon MAMP treatment. Finally, ios1 mutants were defective in BABA-induced resistance and priming. This work reveals IOS1 as a regulatory protein of FLS2- and EFR-mediated signaling that primes PTI activation upon bacterial elicitation.
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