Evidence map›Paper›PMID 25070537›Full record

ArticleMolecular psychiatry2015

Dietary patterns and cognitive decline in an Australian study of ageing.

S L Gardener, S R Rainey-Smith, M B Barnes, H R Sohrabi, M Weinborn, Y Y Lim, K Harrington, K Taddei, Y Gu, A Rembach and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  19. The role of diet in moderating the relationship between symptoms of depression and brain amyloid load.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  20. Review

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

S L Gardener1] Centre of Excellence for Alzheimer's disease Research and Care, School of Medical Sciences, Edith Cowan University, Joondalup, WA, Australia [2] Sir James McCusker Alzheimer's Disease Research Unit (Hollywood Private Hospital), Perth, WA, Australia.
S R Rainey-Smith1] Centre of Excellence for Alzheimer's disease Research and Care, School of Medical Sciences, Edith Cowan University, Joondalup, WA, Australia [2] Sir James McCusker Alzheimer's Disease Research Unit (Hollywood Private Hospital), Perth, WA, Australia.
M B BarnesCSIRO Computational Informatics, Glen Osmond, SA, Australia.
H R Sohrabi1] Centre of Excellence for Alzheimer's disease Research and Care, School of Medical Sciences, Edith Cowan University, Joondalup, WA, Australia [2] Sir James McCusker Alzheimer's Disease Research Unit (Hollywood Private Hospital), Perth, WA, Australia.
M Weinborn1] Centre of Excellence for Alzheimer's disease Research and Care, School of Medical Sciences, Edith Cowan University, Joondalup, WA, Australia [2] Sir James McCusker Alzheimer's Disease Research Unit (Hollywood Private Hospital), Perth, WA, Australia [3] School of Psychology, University of Western Australia, Crawley, WA, Australia.
Y Y LimThe Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.
K HarringtonThe Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.
K Taddei1] Centre of Excellence for Alzheimer's disease Research and Care, School of Medical Sciences, Edith Cowan University, Joondalup, WA, Australia [2] Sir James McCusker Alzheimer's Disease Research Unit (Hollywood Private Hospital), Perth, WA, Australia.
Y Gu1] Taub Institute for Research of Alzheimer's Disease and the Ageing Brain, Columbia University, New York, NY, USA [2] Gertrude H. Sergievsky Centre, Columbia University, New York, NY, USA.
A RembachThe Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.
C SzoekeThe Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.
K A Ellis1] The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia [2] National Ageing Research Institute, Parkville, VIC, Australia [3] Academic Unit for Psychiatry of Old Age, St Vincent's Health, Department of Psychiatry, The University of Melbourne, Kew, VIC, Australia.
C L MastersThe Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.
S L MacaulayCSIRO Preventative Health Flagship, CMSE Parkville, VIC, Australia.
C C RoweDepartment of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, VIC, Australia.
D Ames1] National Ageing Research Institute, Parkville, VIC, Australia [2] Academic Unit for Psychiatry of Old Age, St Vincent's Health, Department of Psychiatry, The University of Melbourne, Kew, VIC, Australia.
J B KeoghSchool of Pharmacy and Medical Sciences and Sansom Institute for Health Research, Division of Health Sciences, University of South Australia, Adelaide, SA, Australia.
N Scarmeas1] Taub Institute for Research of Alzheimer's Disease and the Ageing Brain, Columbia University, New York, NY, USA [2] Gertrude H. Sergievsky Centre, Columbia University, New York, NY, USA [3] Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA [4] Department of Social Medicine, Psychiatry, and Neurology, National and Kapodistrian University of Athens, Athens, Greece.
R N Martins1] Centre of Excellence for Alzheimer's disease Research and Care, School of Medical Sciences, Edith Cowan University, Joondalup, WA, Australia [2] Sir James McCusker Alzheimer's Disease Research Unit (Hollywood Private Hospital), Perth, WA, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this paper was to investigate the association of three well-recognised dietary patterns with cognitive change over a 3-year period. Five hundred and twenty-seven healthy participants from the Australian Imaging, Biomarkers and Lifestyle study of ageing completed the Cancer Council of Victoria food frequency questionnaire at baseline and underwent a comprehensive neuropsychological assessment at baseline, 18 and 36 months follow-up. Individual neuropsychological test scores were used to construct composite scores for six cognitive domains and a global cognitive score. Based on self-reported consumption, scores for three dietary patterns, (1) Australian-style Mediterranean diet (AusMeDi), (2) western diet and (3) prudent diet were generated for each individual. Linear mixed model analyses were conducted to examine the relationship between diet scores and cognitive change in each cognitive domain and for the global score. Higher baseline adherence to the AusMeDi was associated with better performance in the executive function cognitive domain after 36 months in apolipoprotein E (APOE) ɛ4 allele carriers (P<0.01). Higher baseline western diet adherence was associated with greater cognitive decline after 36 months in the visuospatial cognitive domain in APOE ɛ4 allele non-carriers (P<0.01). All other results were not significant. Our findings in this well-characterised Australian cohort indicate that adherence to a healthy diet is important to reduce risk for cognitive decline, with the converse being true for the western diet. Executive function and visuospatial functioning appear to be particularly susceptible to the influence of diet.

Indexed as

DietAgedAgingApolipoprotein E4AustraliaCognition DisordersCohort StudiesExecutive FunctionFemaleFollow-Up StudiesHumansLinear ModelsMaleNeuropsychological TestsPrincipal Component AnalysisSurveys and QuestionnairesApolipoprotein E4

Identifiers

PMID25070537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.