Evidence map›Paper›PMID 25070342›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2014

Quantifying electrical interactions between cardiomyocytes and other cells in micropatterned cell pairs.

Hung Nguyen, Nima Badie, Luke McSpadden, Dawn Pedrotty, Nenad Bursac

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hung NguyenDepartment of Biomedical Engineering, Duke University, 3000 Science Drive, Hudson Hall 136, 90281, Durham, NC, USA.
Nima Badie
Luke McSpadden
Dawn Pedrotty
Nenad Bursac

Funding

Training Program in Cardiovascular Biology and MedicineT32HL007843 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI THOMAS P. CAPPOLA, Sharlene M Day · 1996 to 2026
$11.0M
Function and Integration of Stem Cell-derived Cardiac Tissue PatchR01HL104326 · NHLBI · DUKE UNIVERSITY · PI BURSAC, NENAD · 2010 to 2014
$1.8M
Tissue-engineered Autonomous PacemakerR21HL106203 · NHLBI · DUKE UNIVERSITY · PI BURSAC, NENAD · 2011 to 2012
$421k
NHLBI NIH HHS R01 HL104326NHLBI NIH HHS R01-HL-104326NHLBI NIH HHS R21 HL106203NHLBI NIH HHS R21-HL-106203NHLBI NIH HHS T32 HL007843
6 · The paper itself

Abstract

Micropatterning is a powerful technique to control cell shape and position on a culture substrate. In this chapter, we describe the method to reproducibly create large numbers of micropatterned heterotypic cell pairs with defined size, shape, and length of cell-cell contact. These cell pairs can be utilized in patch clamp recordings to quantify electrical interactions between cardiomyocytes and non-cardiomyocytes.

Indexed as

Cell CommunicationElectrophysiological PhenomenaAction PotentialsHumansMyocytes, CardiacPatch-Clamp Techniques

Identifiers

PMID25070342
PMCPMC4219610

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.