Trial reportPediatrics2014
Growth after adenotonsillectomy for obstructive sleep apnea: an RCT.
Trial report in Pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 139 citations in OpenAlex.
- Short-Term Weight Gain after Tonsillectomy Does Not Lead to Overweight: A Systematic Review.Nutrients · 2024Pooled it
- Postoperative Bleeding and Associated Utilization following Tonsillectomy in Children.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2017Pooled it
- Pooled it
- Tonsillectomy or adenotonsillectomy versus non-surgical management for obstructive sleep-disordered breathing in children.The Cochrane database of systematic reviews · 2015Pooled it
- Growth and sleep outcomes after adenotonsillectomy in pediatric mild sleep-disordered breathing.Scientific reports · 2025Trial
- Impact of adenotonsillectomy on growth trajectories in preschool children with mild-moderate obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Trial
- Trial
- Changes in Body Mass Index Following Pediatric Tonsillectomy for Obstructive Sleep Apnea.Cureus · 2026Article
- Differential effects of adenotonsillectomy on growth and asthma control in children with obstructive sleep apnea and varying body mass index: A prospective cohort study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Craniofacial and dental arch morphological changes in pediatric obstructive sleep apnea syndrome following rapid maxillary expansion.Journal of dental sciences · 2026Article
- Indications for Adenoidectomy and Tonsillectomy for Obstructive Sleep Apnea in Children and Adolescents.Children (Basel, Switzerland) · 2025Review
- Nasal microbiota dysbiosis and functional alterations in children with adenoid hypertrophy: potential biomarkers and post-surgical microbial recovery.Applied microbiology and biotechnology · 2025Article
- Comparative Effectiveness of Preepiglottic Baton Plates and Mandibular Distraction in Infants with Robin Sequence.Plastic and reconstructive surgery · 2025Article
- Weight Gain in Obese Children After Intracapsular Tonsillectomy.Laryngoscope investigative otolaryngology · 2025Article
- Impact of Adenotonsillectomy on Weight Gain in Children: A Systematic Review.Children (Basel, Switzerland) · 2025Review
- Reduced Slow Wave Sleep Is Associated with Increased Risk of Short Stature in Children: A Cross-Sectional Study.Nature and science of sleep · 2025Article
- Long Term Ventilation in Pediatric Central Apnea: Etiologies and Therapeutic Approach over a Decade.Pediatric pulmonology · 2025Article
- Adenotonsillectomy Versus Watchful Waiting for Children with Obstructive Sleep Apnea Syndrome: A Systematic Review with Meta-Analysis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Sleep quality, sleep apnea, and metabolic health in children treated with adenotonsillectomy.Sleep & breathing = Schlaf & Atmung · 2023Article
- Investigating factors influencing post-operative growth in pre-pubertal children after adenotonsillectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 11 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesAdenotonsillectomy for obstructive sleep apnea syndrome (OSAS) may lead to weight gain, which can have deleterious health effects when leading to obesity. However, previous data have been from nonrandomized uncontrolled studies, limiting inferences. This study examined the anthropometric changes over a 7-month interval in a randomized controlled trial of adenotonsillectomy for OSAS, the Childhood Adenotonsillectomy Trial.
methodsA total of 464 children who had OSAS (average apnea/hypopnea index [AHI] 5.1/hour), aged 5 to 9.9 years, were randomized to Early Adenotonsillectomy (eAT) or Watchful Waiting and Supportive Care (WWSC). Polysomnography and anthropometry were performed at baseline and 7-month follow-up. Multivariable regression modeling was used to predict the change in weight and growth indices.
resultsInterval increases in the BMI z score (0.13 vs. 0.31) was observed in both the WWSC and eAT intervention arms, respectively, but were greater with eAT (P < .0001). Statistical modeling showed that BMI z score increased significantly more in association with eAT after considering the influences of baseline weight and AHI. A greater proportion of overweight children randomized to eAT compared with WWSC developed obesity over the 7-month interval (52% vs. 21%; P < .05). Race, gender, and follow-up AHI were not significantly associated with BMI z score change.
conclusionseAT for OSAS in children results in clinically significant greater than expected weight gain, even in children overweight at baseline. The increase in adiposity in overweight children places them at further risk for OSAS and the adverse consequences of obesity. Monitoring weight, nutritional counseling, and encouragement of physical activity should be considered after eAT for OSAS.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.