ArticlePediatrics2014
Delayed diagnosis of critical congenital heart defects: trends and associated factors.
Article in Pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 122 citations in OpenAlex.
- Characteristics of children with congenital heart defects and their caregivers in three U.S. sites: the Congenital Heart Survey To Recognize Outcomes Needs and well-beinG of KIDS (CHSTRONG KIDS).Progress in pediatric cardiology · 2026Article
- Congenital Heart Defects, Special Needs, and Developmental Vulnerability in Singleton Children at School Age: A Population-Based Data Linkage Study.Journal of the American Heart Association · 2026Article
- Implementation of a coarctation personalized longitudinal algorithm for newborns (Coarc-PLAN) in the care of patients with prenatal concern for coarctation of the aorta.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Newborn Critical Congenital Heart Disease Screening Using Pulse Oximetry in a Global Context: Progress, Disparities, and the Importance of Early Detection.International journal of neonatal screening · 2026Article
- Cognitive disengagement syndrome and peer relationships of youth with critical congenital heart defects.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2025Article
- Prevalence of congenital heart defects among children with and without diagnosed fetal alcohol spectrum disorders, 2016-2022.Drug and alcohol dependence · 2025Article
- Article
- Newborn Screening for Congenital Heart Disease: A Five-Year Study in Shanghai.International journal of neonatal screening · 2025Article
- Cardiac-related neonatal collapse presenting to the emergency department: a retrospective cohort study.BMJ paediatrics open · 2025Article
- Evaluation of Integrated Service Strategy Based on Diagnosis of Duct-Dependent Congenital Heart Disease and Neonatal Mortality Data Analysis - Beijing, China, 2021-2022.China CDC weekly · 2025Article
- The Performance of Critical Congenital Heart Disease Screening in Rural Versus Urban Locations in the Northwest United States.Journal of pediatrics. Clinical practice · 2024Article
- Automated analysis of heart sound signals in screening for structural heart disease in children.European journal of pediatrics · 2024Article
- Expanding the Massachusetts Birth Defects Monitoring Program to include additional pregnancy outcomes: Programmatic efforts and impacts on case ascertainment, 2012-2020.Birth defects research · 2024Article
- Neonatal Outcomes of Critical Congenital Heart Defects: A Multicenter Epidemiological Study of Turkish Neonatal Society : Neonatal Outcomes of CCHD.Pediatric cardiology · 2024Article
- A case of a young man with secondary hypertension.Qatar medical journal · 2024Article
- Non-Invasive Imaging Assessment in Patients with Aortic Coarctation: A Contemporary Review.Journal of clinical medicine · 2023Review
- A multicenter study on two-stage transfer learning model for duct-dependent CHDs screening in fetal echocardiography.NPJ digital medicine · 2023Article
- Outpatient pediatric cardiology consultations in a tertiary academic hospital.Journal of family medicine and primary care · 2023Article
- Early Echocardiography Predicts Intervention Need in Antenatal Suspicion of Coarctation of the Aorta.CJC pediatric and congenital heart disease · 2022Article
- Impact of an electronic medical record-based automated screening program for critical congenital heart disease: Emirates Health Services, United Arab Emirates.BMC medical informatics and decision making · 2022Observational
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveWe aimed to examine trends in timing of diagnosis of critical congenital heart defects (CCHDs) and factors associated with delayed diagnosis (diagnosis after discharge home following delivery).
methodsWe examined a population-based retrospective cohort of CCHD cases among live births identified through the Massachusetts Birth Defects Monitoring Program. Congenital heart defects were considered critical if the infant received corrective surgery, interventional catheterization, palliative care, or died as a result of the defect within 12 months of birth. Timing of initial diagnosis was classified as prenatal, postnatal before discharge home, or delayed. Demographic, perinatal, and mortality information was obtained from the Registry of Vital Records and Statistics. Prevalence ratios (PRs) were used to examine associations with delayed diagnosis.
resultsAmong 460 467 live births to Massachusetts residents between 2004 and 2009, we identified 916 CCHD cases, of which 126 (13.8%) had delayed diagnosis. Rates of prenatal CCHD diagnosis increased from 44.9% in 2004 to 63.8% in 2009, whereas rates of delayed diagnosis decreased from 17.1% to 10.6% over the same time period. Among cases with delayed diagnosis, the most common defects were coarctation, pulmonary valve stenosis, and tetralogy of Fallot. Delayed diagnosis was associated with delivery outside a tertiary hospital (adjusted PR: 3.6 [95% confidence interval: 2.5-5.2]) and isolated CCHD (adjusted PR: 1.7 [95% confidence interval: 1.1-2.7]).
conclusionsDespite increasing prenatal diagnosis of CCHDs, delayed diagnosis still occurs in over 10% of cases. Understanding factors associated with delayed diagnosis could help to improve prenatal and postnatal screening efforts, including pulse oximetry testing.
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