Evidence map›Paper›PMID 25070156›Full record

ArticleCell research2014

Blood loses it when nerves go bad.

Ninib Baryawno, David T Scadden

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ninib Baryawno1] Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA [2] Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA [3] Harvard Stem Cell Institute, Cambridge, MA 02138, USA.
David T Scadden1] Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA [2] Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA [3] Harvard Stem Cell Institute, Cambridge, MA 02138, USA.
Massachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myeloproliferative neoplasms are diseases that arise in the stem cells of the blood. In a recent paper published in Nature, Arranz et al. demonstrated that abrogation of sympathetic nerve fibers reduced bone marrow Nestin mesenchymal cells, which in turn led to an expansion of hematopoietic stem cells and progression of myeloproliferative neoplasms.

Indexed as

Stem Cell NicheAnimalsFemaleHematopoietic Stem CellsHumansMyeloproliferative DisordersNeoplasmsNerve FibersSympathetic Nervous System

Identifiers

PMID25070156
PMCPMC4185357
OpenAlexW1994938553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.