Evidence map›Paper›PMID 25070067›Full record

ArticleJAMA pediatrics2014

An electronic screen for triaging adolescent substance use by risk levels.

Sharon Levy, Roger Weiss, Lon Sherritt, Rosemary Ziemnik, Allegra Spalding, Shari Van Hook, Lydia A Shrier

Open access · greenAbstract read
In one paragraph

Article in JAMA pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 1 synthesis or guideline pooled it, 205 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  6. Intimate violence as it relates to risky sexual behavior among at-risk females.Psychological trauma : theory, research, practice and policy · 2018
    Trial
  7. Review
  8. Article
  9. Adolescent Substance Use Screening in the Emergency Department.Journal of the American College of Emergency Physicians open · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Substance Use Screening Among Adolescents: National Dental Practice-Based Research Network Survey.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article
  15. U.S. Pediatricians' Attitudes and Practices Around Screening for Substance Use in Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article
  16. Article
  17. An Innovative Youth-Friendly Electronic Questionnaire to Identify Mental, Sexual and Reproductive Health Risks: A Validation Study of the Total Teen Assessment.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  18. Article
  19. Article
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sharon LevyAdolescent Substance Abuse Program, Boston Children's Hospital, Boston, Massachusetts2Division of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts3Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
Roger WeissDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts5Division of Alcohol and Drug Abuse, McLean Hospital, Belmont, Massachusetts.
Lon SherrittDivision of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts3Department of Pediatrics, Harvard Medical School, Boston, Massachusetts6Center for Adolescent Substance Abuse Research, Boston Children's Hospital, Boston, Massachusetts.
Rosemary ZiemnikAdolescent Substance Abuse Program, Boston Children's Hospital, Boston, Massachusetts2Division of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts.
Allegra SpaldingDivision of Adolescent/Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts.
Shari Van HookAdolescent Substance Abuse Program, Boston Children's Hospital, Boston, Massachusetts2Division of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts3Department of Pediatrics, Harvard Medical School, Boston, Massachusetts6Center for.
Lydia A ShrierDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts7Division of Adolescent/Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts.
Boston Children's Hospital · USHarvard University · USMcLean Hospital · US

Funding

The National Drug Abuse Treatment Clinical Trials Network (U10)U10DA015831 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI CARROLL, KATHLEEN M., WEISS, ROGER D. · 2002 to 2015
$28.8M
Mentoring in Drug Abuse and Dual Diagnosis ResearchK24DA022288 · NIDA · MCLEAN HOSPITAL · PI WEISS, ROGER D. · 2007 to 2016
$1.8M
Mentored Clinical Career Award in Adolescent Substance AbuseK23DA019570 · NIDA · BOSTON CHILDREN'S HOSPITAL · PI LEVY, SHARON J · 2007 to 2012
$921k
NIDA NIH HHS K23 DA019570NIDA NIH HHS K24 DA022288NIDA NIH HHS K24DA022288NIDA NIH HHS U10 DA015831NIDA NIH HHS U10DA15831PHS HHS D55HP23194
6 · The paper itself

Abstract

importanceScreening adolescents for substance use and intervening immediately can reduce the burden of addiction and substance-related morbidity. Several screening tools have been developed to identify problem substance use for adolescents, but none have been calibrated to triage adolescents into clinically relevant risk categories to guide interventions.

objectiveTo describe the psychometric properties of an electronic screen and brief assessment tool that triages adolescents into 4 actionable categories regarding their experience with nontobacco substance use. DESIGN, SETTING, AND

participantsAdolescent patients (age range, 12-17 years) arriving for routine medical care at 2 outpatient primary care centers and 1 outpatient center for substance use treatment at a pediatric hospital completed an electronic screening tool from June 1, 2012, through March 31, 2013, that consisted of a question on the frequency of using 8 types of drugs in the past year (Screening to Brief Intervention). Additional questions assessed severity of any past-year substance use. Patients completed a structured diagnostic interview (Composite International Diagnostic Interview-Substance Abuse Module), yielding Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) substance use diagnoses. MAIN OUTCOMES AND MEASURES: For the entire screen and the Screening to Brief Intervention, sensitivity and specificity for identifying nontobacco substance use, substance use disorders, severe substance use disorders, and tobacco dependence were calculated using the Composite International Diagnostic Interview-Substance Abuse Module as the criterion standard.

resultsOf 340 patients invited to participate, 216 (63.5%) enrolled in the study. Sensitivity and specificity were 100% and 84% (95% CI, 76%-89%) for identifying nontobacco substance use, 90% (95% CI, 77%-96%) and 94% (95% CI, 89%-96%) for substance use disorders, 100% and 94% (95% CI, 90%-96%) for severe substance use disorders, and 75% (95% CI, 52%-89%) and 98% (95% CI, 95%-100%) for nicotine dependence. No significant differences were found in sensitivity or specificity between the full tool and the Screening to Brief Intervention. CONCLUSIONS AND RELEVANCE: A single screening question assessing past-year frequency use for 8 commonly misused categories of substances appears to be a valid method for discriminating among clinically relevant risk categories of adolescent substance use.

Indexed as

Sickness Impact ProfileAdolescentAdolescent BehaviorChildFemaleHumansMaleMass ScreeningRisk AssessmentSensitivity and SpecificitySubstance-Related DisordersSurveys and QuestionnairesTriage

Identifiers

PMID25070067
PMCPMC4270364
OpenAlexW2137138400

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.