Trial reportCritical care (London, England)2014
Early mobilization on continuous renal replacement therapy is safe and may improve filter life.
Trial report in Critical care (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Factors influencing physical activity and rehabilitation in survivors of critical illness: a systematic review of quantitative and qualitative studies.Intensive care medicine · 2017Pooled it
- Non anti-coagulant factors associated with filter life in continuous renal replacement therapy (CRRT): a systematic review and meta-analysis.BMC nephrology · 2017Pooled it
- Safety criteria to start early mobilization in intensive care units. Systematic review.Revista Brasileira de terapia intensivaPooled it
- Association between Blood Potassium Level and Recovery of Postoperative Gastrointestinal Motility during Continuous Renal Replacement Therapy in Patient Undergoing Open Abdominal Surgery.BioMed research international · 2019Trial
- Rehabilitation and the post-intensive care syndrome across the recovery continuum: a narrative review.Intensive care medicine · 2026Review
- How to safeguard the continuous renal replacement therapy circuit: a narrative review.Frontiers in medicine · 2024Review
- Continuous Renal Replacement Therapy in Critically Ill Children.Turkish archives of pediatrics · 2022Article
- Intra-dialytic hypotension following the transition from continuous to intermittent renal replacement therapy.Annals of intensive care · 2021Article
- Decreased CRRT Filter Lifespan in COVID-19 ICU Patients.Journal of clinical medicine · 2021Article
- Frailty status among older critically ill patients with severe acute kidney injury.Critical care (London, England) · 2021Article
- A cross-sectional study of early mobility practice in intensive care units in Sarawak Hospitals, Malaysia.Nursing open · 2021Article
- Walking While Dialyzing: A Retrospective Observation of Early Mobility and Ambulation for Patients on Continuous Renal Replacement Therapy.Critical care explorations · 2020Article
- Safety, Feasibility, and Efficacy of Early Rehabilitation in Patients Requiring Continuous Renal Replacement: A Quality Improvement Study.Kidney international reports · 2020Article
- Low Levels of Physical Activity During Critical Illness and Weaning: The Evidence-Reality Gap.Journal of intensive care medicine · 2019Observational
- [PROtocol-based MObilizaTION on intensive care units : Design of a cluster randomized pilot study].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2018Article
- Physical rehabilitation interventions in the intensive care unit: a scoping review of 117 studies.Journal of intensive care · 2018Article
- What makes weekend allied health services effective and cost-effective (or not) in acute medical and surgical wards? Perceptions of medical, nursing, and allied health workers.BMC health services research · 2017Article
- [Physiotherapy interventions in the ICU : Outcome-relevant measurement parameters].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2017Review
- [Algorithms for early mobilization in intensive care units].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2017Article
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDespite studies demonstrating benefit, patients with femoral vascular catheters placed for continuous renal replacement therapy are frequently restricted from mobilization. No researchers have reported filter pressures during mobilization, and it is unknown whether mobilization is safe or affects filter lifespan. Our objective in this study was to test the safety and feasibility of mobilization in this population.
methodsA total of 33 patients undergoing continuous renal replacement therapy via femoral, subclavian or internal jugular vascular access catheters at two general medical-surgical intensive care units in Australia were enrolled. Patients underwent one of three levels of mobilization intervention as appropriate: (1) passive bed exercises, (2) sitting on the bed edge or (3) standing and/or marching. Catheter dislodgement, haematoma and bleeding during and following interventions were evaluated. Filter pressure parameters and lifespan (hours), nursing workload and concern were also measured.
resultsNo episodes of filter occlusion or failure occurred during any of the interventions. No adverse events were detected. The intervention filters lasted longer than the nonintervention filters (regression coefficient = 13.8 (robust 95% confidence interval (CI) = 5.0 to 22.6), P = 0.003). In sensitivity analyses, we found that filter life was longer in patients who had more position changes (regression coefficient = 2.0 (robust 95% CI = 0.6 to 3.5), P = 0.007). The nursing workloads between the intervention shift and the following shift were similar.
conclusionsMobilization during renal replacement therapy via a vascular catheter in patients who are critically ill is safe and may increase filter life. These findings have significant implications for the current mobility restrictions imposed on patients with femoral vascular catheters for renal replacement therapy.
trial registrationAustralian and New Zealand Clinical Trials Registry ACTRN12611000733976 (registered 13 July 2011).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.