ArticleBehavioral and brain functions : BBF2014
Fatigue correlates with the decrease in parasympathetic sinus modulation induced by a cognitive challenge.
Article in Behavioral and brain functions : BBF, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- A systematic review of the prevalence of fatigue in common mental disorders (mood disorders, anxiety disorders, personality disorders, and trauma and stressor related disorders).BMC psychiatry · 2026Pooled it
- Enhanced cardiac vagal tone in mental fatigue: Analysis of heart rate variability in Time-on-Task, recovery, and reactivity.PloS one · 2021Article
- Mental fatigue is linked with attentional bias for sad stimuli.Scientific reports · 2019Article
- Article
- Non-restorative Sleep Caused by Autonomic and Electroencephalography Parameter Dysfunction Leads to Subjective Fatigue at Wake Time in Shift Workers.Frontiers in neurology · 2019Article
- Cross-Modal Conflict Increases With Time-on-Task in a Temporal Discrimination Task.Frontiers in psychology · 2019Article
- Task-relevant cognitive and motor functions are prioritized during prolonged speed-accuracy motor task performance.Experimental brain research · 2018Article
- DSM-5 Criteria and Depression Severity: Implications for Clinical Practice.Frontiers in psychiatry · 2018Article
- The combined fatigue effects of sequential exposure to seated whole body vibration and physical, mental, or concurrent work demands.PloS one · 2017Article
- Music Improves Subjective Feelings Leading to Cardiac Autonomic Nervous Modulation: A Pilot Study.Frontiers in neuroscience · 2017Article
- Frontier studies on fatigue, autonomic nerve dysfunction, and sleep-rhythm disorder.The journal of physiological sciences : JPS · 2015Review
- Fatigue in chronic inflammation - a link to pain pathways.Arthritis research & therapy · 2015Review
- Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life.Medical gas researchArticle
- Evaluation of Fatigue in Cancer Patients in An Area Affected by The Great East Japan Earthquake.Asia-Pacific journal of oncology nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is known that enhancement of sympathetic nerve activity based on a decrease in parasympathetic nerve activity is associated with fatigue induced by mental tasks lasting more than 30 min. However, to measure autonomic nerve function and assess fatigue levels in both clinical and industrial settings, shorter experimental durations and more sensitive measurement methods are needed. The aim of the present study was to establish an improved method for inducing fatigue and evaluating the association between it and autonomic nerve activity.
methodsTwenty-eight healthy female college students participated in the study. We used a kana pick-out test (KPT) as a brief verbal cognitive task and recorded electrocardiography (ECG) to measure autonomic nerve activity. The experimental design consisted of a 16-min period of ECG: A pre-task resting state with eyes open for 3 min and eyes closed for 3 min, the 4-min KPT, and a post-task resting state with eyes open for 3 min and eyes closed for 3 min.
resultsBaseline fatigue sensation, measured by a visual analogue scale before the experiment, was associated with the decrease in parasympathetic sinus modulation, as indicated the by ratio of low-frequency component power (LF) to high-frequency component power (HF), during the KPT. The LF/HF ratio during the post-KPT rest with eyes open tended to be greater than the ratio during the KPT and correlated with fatigue sensation. Fatigue sensation was correlated negatively with log-transformed HF, which is an index of parasympathetic sinus modulation, during the post-KPT rest with eyes open.
conclusionsThe methods described here are useful for assessing the association between fatigue sensation and autonomic nerve activity using a brief cognitive test in healthy females.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.