Evidence map›Paper›PMID 25068917›Full record

ArticleEpidemiology and infection2015

Reinfection after successful eradication of Helicobacter pylori in three different populations in Alaska.

M G Bruce, D L Bruden, J M Morris, A L Reasonover, F Sacco, D Hurlburt, T W Hennessy, J Gove, A Parkinson, G Sahagun and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Increasing our knowledge about the epidemiology ofInternational journal of circumpolar health · 2024
    Article
  5. Article
  6. Przeglad gastroenterologiczny · 2024
    Article
  7. [The Recurrence ofThe Korean journal of helicobacter and upper gastrointestinal research · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Presence ofJournal of medical microbiology · 2020
    Article
  12. Long-term follow-up ofEmerging microbes & infections · 2020
    Observational
  13. Article
  14. Helicobacter pylori recrudescence and its influencing factors.Journal of cellular and molecular medicine · 2019
    Review
  15. H. pylori-associated pathologic findings among Alaska native patients.International journal of circumpolar health · 2018
    Article
  16. Article
  17. Article
  18. Novel and Effective Therapeutic Regimens forFrontiers in cellular and infection microbiology · 2017
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

M G BruceArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging Zoonotic and Infectious Diseases,Centers for Disease Control and Prevention (CDC),Anchorage, Alaska,USA.
D L BrudenArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging Zoonotic and Infectious Diseases,Centers for Disease Control and Prevention (CDC),Anchorage, Alaska,USA.
J M MorrisArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging Zoonotic and Infectious Diseases,Centers for Disease Control and Prevention (CDC),Anchorage, Alaska,USA.
A L ReasonoverArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging Zoonotic and Infectious Diseases,Centers for Disease Control and Prevention (CDC),Anchorage, Alaska,USA.
F SaccoThe Alaska Native Medical Center,Anchorage, Alaska,USA.
D HurlburtArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging Zoonotic and Infectious Diseases,Centers for Disease Control and Prevention (CDC),Anchorage, Alaska,USA.
T W HennessyArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging Zoonotic and Infectious Diseases,Centers for Disease Control and Prevention (CDC),Anchorage, Alaska,USA.
J GoveLiver Disease and Hepatitis Program, Division of Community Health Services,Alaska Native Tribal Health Consortium,Anchorage, Alaska,USA.
A ParkinsonArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging Zoonotic and Infectious Diseases,Centers for Disease Control and Prevention (CDC),Anchorage, Alaska,USA.
G SahagunInternal Medicine Associate Inc., Anchorage,Alaska,USA.
P DavisThe Alaska Native Medical Center,Anchorage, Alaska,USA.
J KlejkaYukon Kuskokwim Health Corporation,Bethel, Alaska,USA.
B J McMahonArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging Zoonotic and Infectious Diseases,Centers for Disease Control and Prevention (CDC),Anchorage, Alaska,USA.
National Center for Emerging and Zoonotic Infectious Diseases · USCenters for Disease Control and Prevention · USAlaska Native Medical Center · USAlaska Native Tribal Health Consortium · USAnchorage Associates in Radiation Medicine · USYukon Kuskokwim Health Corporation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed a study to determine rates of reinfection in three groups followed for 2 years after successful treatment: American Indian/Alaska Native (AI/AN) persons living in urban (group 1) and rural (group 2) communities, and urban Alaska non-Native persons (group 3). We enrolled adults diagnosed with H. pylori infection based on a positive urea breath test (13C-UBT). After successful treatment was documented at 2 months, we tested each patient by 13C-UBT at 4, 6, 12 and 24 months. At each visit, participants were asked about medication use, illnesses and risk factors for reinfection. We followed 229 persons for 2 years or until they became reinfected. H. pylori reinfection occurred in 36 persons; cumulative reinfection rates were 14·5%, 22·1%, and 12·0% for groups 1, 2, and 3, respectively. Study participants who became reinfected were more likely to have peptic ulcer disease (P = 0·02), low education level (P = 0·04), or have a higher proportion of household members infected with H. pylori compared to participants who did not become reinfected (P = 0·03). Among all three groups, reinfection occurred at rates higher than those reported for other US populations (<5% at 2 years); rural AI/AN individuals appear to be at highest risk for reinfection.

Indexed as

Helicobacter pyloriAlaskaEducational StatusFamily CharacteristicsFemaleHelicobacter InfectionsHumansIndians, North AmericanMaleMiddle AgedRecurrenceRisk FactorsRural PopulationUrban Populationreinfection

Identifiers

PMID25068917
PMCPMC9507161
OpenAlexW2141573101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.