Evidence map›Paper›PMID 25068720›Full record

SynthesisPloS one2014

Global burden of HIV among men who engage in transactional sex: a systematic review and meta-analysis.

Catherine E Oldenburg, Amaya G Perez-Brumer, Sari L Reisner, Jason Mattie, Till Bärnighausen, Kenneth H Mayer, Matthew J Mimiaga

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Examining HIV Knowledge and Sexually Risky Behaviors among Female Sex Workers in Kampala, Uganda.International journal of environmental research and public health · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Catherine E OldenburgDepartment of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America; The Fenway Institute, Fenway Community Health, Boston, Massachusetts, United States of America.
Amaya G Perez-BrumerDepartment of Sociomedical Sciences, Columbia Mailman School of Public Health, New York, New York, United States of America.
Sari L ReisnerDepartment of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America; The Fenway Institute, Fenway Community Health, Boston, Massachusetts, United States of America.
Jason MattieThe Fenway Institute, Fenway Community Health, Boston, Massachusetts, United States of America.
Till BärnighausenDepartment of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts, United States of America; Africa Centre for Health and Population Science, Mtubatuba, South Africa.
Kenneth H MayerThe Fenway Institute, Fenway Community Health, Boston, Massachusetts, United States of America; Department of Medicine, Beth Israel Deaconess, Boston, Massachusetts, United States of America.
Matthew J MimiagaDepartment of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America; The Fenway Institute, Fenway Community Health, Boston, Massachusetts, United States of America; Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

Funding

Epidemiology of Infectious Diseases and BiodefenseT32AI007535 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GRAD, YONATAN H, MURRAY, MEGAN B · 1998 to 2025
$4.8M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
GSH Training GrantT32HD049339 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jennifer S Hirsch · 2006 to 2026
$3.4M
HIV Risk for MSM Sex Workers: A Social, Sexual, & Drug Network Simulation StudyR21DA035113 · NIDA · FENWAY COMMUNITY HEALTH CENTER · PI BIELLO, KATIE BROOKS · 2013 to 2014
$465k
Technology for HIV Prevention Among Vulnerable Men in IndiaR21DA033720 · NIDA · FENWAY COMMUNITY HEALTH CENTER · PI MIMIAGA, MATTHEW JAMES · 2011 to 2012
$465k
NIAID NIH HHS T32 AI007535NIAID NIH HHS T32AI007535NICHD NIH HHS T32 HD049339NIDA NIH HHS R21 DA033720NIDA NIH HHS R21DA033720NIDA NIH HHS R21 DA035113NIDA NIH HHS R21DA035113NIMH NIH HHS R25 MH083620Wellcome Trust 097410
6 · The paper itself

Abstract

backgroundMen who engage in transactional sex, the exchange of sex for money, goods, or other items of value, are thought to be at increased risk of HIV, but there have been no systematic attempts to characterize HIV burden in this population. We undertook a systematic review and meta-analysis to quantify the burden in this population compared with that of men in the general population to better inform future HIV prevention efforts.

methodsWe searched seven electronic databases, national surveillance reports, and conference abstracts for studies of men who engage in transactional sex published between 2004-2013. Random effects meta-analysis was used to determine pooled HIV prevalence and prevalence ratios (PR) for the difference in HIV prevalence among men who engage in transactional sex as compared to general population men.

findingsOf 66 studies included representing 31,924 men who had engaged in transactional sex in 28 countries, pooled biological assay-confirmed HIV prevalence was 10.5% (95% CI = 9.4 to 11.5%). The highest pooled HIV prevalence was in Sub-Saharan Africa (31.5%, 95% CI = 21.6 to 41.5%), followed by Latin America (19.3%, 95% CI = 15.5 to 23.1%), North America (16.6%, 95% CI = 3.7 to 29.5%), and Europe (12.2%, 95% CI = 6.0 to 17.2%). Men who engaged in transactional sex had an elevated burden of HIV compared to the general male population (PR = 20.7, 95% CI = 16.8 to 25.5).

conclusionsThe global burden of HIV is disproportionately high among men who engage in transactional sex compared with the general male population. There is an urgent need to include this population in systematic surveillance as well as to scale-up access to quality HIV prevention programs.

Indexed as

Cost of IllnessSexual PartnersFemaleHIV InfectionsHomosexuality, MaleHumansMalePopulation SurveillancePrevalenceSex Workers

Identifiers

PMID25068720
PMCPMC4113434

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.