Evidence map›Paper›PMID 25068670›Full record

ArticleNeuropsychology2015

Prospective and episodic memory in relation to hippocampal volume in adults with spina bifida myelomeningocele.

Amery Treble-Barna, Jenifer Juranek, Karla K Stuebing, Paul T Cirino, Maureen Dennis, Jack M Fletcher

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Neuropsychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06560788 (Chiari II Brain Malformation), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06560788 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Chiari II Brain Malformation: The Role of Cerebrospinal Fluid in Neurodevelopmental Defects Associated With Spina Bifida

Typeobservational_patient_registrySponsorUniversity College, LondonRan2024 to 2027Enrolled18ConditionsMyelomeningocele, Brain Malformation, Chiari Malformation Type 2Armscollection of cerebrospinal fluid
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Long-term cognitive outcomes of Chiari II malformation and corpus callosum abnormalities in myelomeningocele.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Spina bifida.Nature reviews. Disease primers · 2015
    Review
  12. Neuropsychological care guidelines for people with spina bifida.Journal of pediatric rehabilitation medicine
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Amery Treble-BarnaDepartment of Psychology, University of Houston.
Jenifer JuranekDepartment of Pediatrics, Children's Learning Institute, University of Texas Health Science Center at Houston.
Karla K StuebingTexas Institute for Measurement, Evaluation, and Statistics, University of Houston.
Paul T CirinoDepartment of Psychology, University of Houston.
Maureen DennisProgram in Neurosciences and Mental Health, Department of Psychology, The Hospital for Sick Children.
Jack M FletcherDepartment of Psychology, University of Houston.
University of Houston · USHospital for Sick Children · CAThe University of Texas Health Science Center at Houston · US

Funding

SUBJECT RECRUITMENT AND EVALUATION COREP01HD035946 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FLETCHER, JACK M · 1998 to 2009
$10.8M
NICHD NIH HHS P01 HD035946
6 · The paper itself

Abstract

The present study examined prospective and episodic memory in relation to age, functional independence, and hippocampal volume in younger to middle-aged adults with spina bifida myelomeningocele (SBM) and typically developing (TD) adults. Prospective and episodic memory, as well as hippocampal volume, was reduced in adults with SBM relative to TD adults. Neither memory performance nor hippocampal volume showed greater decrements in older adults. Lower hippocampal volume was associated with reduced prospective memory in adults with SBM, and this relation was specific to the hippocampus and not to a contrast structure, the amygdala. Prospective memory mediated the relation between hippocampal volume and functional independence in adults with SBM. The results add to emerging evidence for reduced memory function in adults with SBM and provide quantitative evidence for compromised hippocampal macrostructure as a neural correlate of reduced memory in this population.

Indexed as

Memory, EpisodicActivities of Daily LivingAdultAgedFemaleHippocampusHumansIndependent LivingMemory DisordersMeningomyeloceleMiddle AgedOrgan SizeSpinal Dysraphism

Identifiers

PMID25068670
PMCPMC4286421
OpenAlexW2328231244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.