Evidence map›Paper›PMID 25068456›Full record

Trial reportHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2014

Associations of weight stigma with cortisol and oxidative stress independent of adiposity.

A Janet Tomiyama, Elissa S Epel, Trissa M McClatchey, Gina Poelke, Margaret E Kemeny, Shannon K McCoy, Jennifer Daubenmier

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 6 pooled it
20.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 6 syntheses or guidelines pooled it, 158 citations in OpenAlex.

  1. Pooled it
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  10. Energy constraint on human health.Trends in endocrinology and metabolism: TEM · 2026
    Review
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  15. Examining the Relationship Between Weight Stigma, Diabetes Stigma, and HbA1c in Adults with Type 2 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Article
  16. Observational
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

A Janet TomiyamaDepartment of Psychology, University of California, Los Angeles.
Elissa S EpelDepartment of Psychiatry, University of California, San Francisco.
Trissa M McClatcheyBaylor College of Medicine.
Gina PoelkeDepartment of Psychiatry, University of California, San Francisco.
Margaret E KemenyDepartment of Psychiatry, University of California, San Francisco.
Shannon K McCoyDepartment of Psychology, University of Maine.
Jennifer DaubenmierOsher Center for Integrative Medicine, University of California, San Francisco.
University of California, San Francisco · USBaylor College of Medicine · USUniversity of California, Los Angeles · USUniversity of Maine · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Effects of Mind-Body Interventions on Metabolic Syndrome RiskK01AT004199 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DAUBENMIER, JENNIFER JOAN · 2007 to 2011
$626k
NCCIH NIH HHS K01 AT004199NCCIH NIH HHS K01AT004199NCRR NIH HHS UL1 RR024131NCRR NIH HHS ULI RR024131
6 · The paper itself

Abstract

objectiveWeight discrimination is associated with increased risk of obesity. The mechanism of this relationship is unknown, but being overweight is a highly stigmatized condition and may be a source of chronic stress that contributes to the development and pathophysiology of obesity. The objective of this study was to test whether weight stigma is associated with physiological risk factors linked to stress and obesity, including hypercortisolism and oxidative stress, independent of adiposity.

methodWe examined the frequency of experiencing situations involving weight stigma and consciousness of weight stigma in relation to hypothalamic--pituitary--adrenal axis activity and oxidative stress (F₂-isoprostanes) in 45 healthy overweight to obese women.

resultsIndependent of abdominal fat, weight stigma was significantly related to measures of cortisol (including salivary measures of cortisol awakening response and serum morning levels) as well as higher levels of oxidative stress. Perceived stress mediated the relationship between weight stigma consciousness and the cortisol awakening response.

conclusionThese preliminary findings show that weight stigma is associated with greater biochemical stress, independent of level of adiposity. It is possible that weight stigma may contribute to poor health underlying some forms of obesity.

Indexed as

StereotypingAdiposityAdultFemaleHumansHydrocortisoneHypothalamo-Hypophyseal SystemMiddle AgedObesityOverweightOxidative StressPituitary-Adrenal SystemSalivaStress, PsychologicalYoung AdultHydrocortisone

Identifiers

PMID25068456
PMCPMC4677673
OpenAlexW2115219805

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.