ArticleScientific reports2014
Plant cells use auxin efflux to explore geometry.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 15 citations in OpenAlex.
- Aggregates-on-chip: a microfluidic device for crowding plant cells in culture.Frontiers in plant science · 2026Article
- Microfluidics-Based Bioassays and Imaging of Plant Cells.Plant & cell physiology · 2021Review
- Review
- Design of a comprehensive microfluidic and microscopic toolbox for the ultra-wide spatio-temporal study of plant protoplasts development and physiology.Plant methods · 2019Article
- Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell movement is the central mechanism for animal morphogenesis. Plant cell development rather relies on flexible alignment of cell axis adjusting cellular differentiation to directional cues. As central input, vectorial fields of mechanical stress and gradients of the phytohormone auxin have been discussed. In tissue contexts, mechanical and chemical signals will always act in concert; experimentally it is difficult to dissect their individual roles. We have designed a novel approach, based on cells, where directionality has been eliminated by removal of the cell wall. We impose a new axis using a microfluidic set-up to generate auxin gradients. Rectangular microvessels are integrated orthogonally with the gradient. Cells in these microvessels align their new axis with microvessel geometry before touching the wall. Auxin efflux is necessary for this touch-independent geometry exploration and we suggest a model, where auxin gradients can be used to align cell axis in tissues with minimized mechanical tensions.
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Registered trials
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