Evidence map›Paper›PMID 25068101›Full record

ArticleGlobal heart2013

The Associations of Indices of Obesity with Lipoprotein Subfractions in Japanese American, African American and Korean Men.

Nobutaka Hirooka, Chol Shin, Kamal H Masaki, Daniel Edmundowicz, Jina Choo, Emma J M Barinas-Mitchell, Bradley J Willcox, Kim Sutton-Tyrrell, Aiman El-Saed, Iva Miljkovic-Gacic and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Global heart, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Optimal serum cholesterol concentrations are associated with accelerated bone loss in African ancestry men.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 4 countries.

Nobutaka HirookaFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Chol ShinFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Kamal H MasakiFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Daniel EdmundowiczFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Jina ChooFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Emma J M Barinas-MitchellFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Bradley J WillcoxFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Kim Sutton-TyrrellFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Aiman El-SaedFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Iva Miljkovic-GacicFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Takayoshi OhkuboFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Katsuyuki MiuraFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Hirotsugu UeshimaFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Lewis H KullerFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
Akira SekikawaFamily Medicine Faculty Development Fellowship, University of Pittsburgh, Pittsburgh, PA, USA (NH), Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea (CS), Department of Geriatric Medicine, University of Hawaii John A. Burns School of Medcine, HI, USA (KHM, BJW), Department of Medicine, Temple University, Philadelphia, PA, USA (DE), College of Nursing, Korea University, Seoul, South Korea (JC), Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA (EJMB, KS, IM, LHK, AS), College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia (AE), Department of Health Science, Shiga University of Medical Science, Otsu, Japan (TO, KM, HU).
University of Pittsburgh · USShiga University of Medical Science · JPUniversity of Hawaiʻi at Mānoa · USAnsan University · KRKing Saud bin Abdulaziz University for Health Sciences · SAKorea University · KRTemple University · US

Funding

Foreign CohortR01HL068200 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SEKIKAWA, AKIRA · 2003 to 2012
$5.6M
Epidemiology of CHD of Men Aged 40+ in US, Hawaii, JapanR01HL071561 · NHLBI · PACIFIC HEALTH RESEARCH INSTITUTE · PI CURB, JESS DAVID · 2003 to 2006
$1.7M
NHLBI NIH HHS R01 HL068200NHLBI NIH HHS R01 HL071561
6 · The paper itself

Abstract

backgroundBoth indices of obesity and lipoprotein subfractions contribute to coronary heart disease risk. However, associations between indices of obesity and lipoprotein subfractions remain undetermined across different ethnic groups. This study aims to examine the associations of indices of obesity in Japanese Americans (JA), African Americans (AA) and Koreans with lipoprotein subfractions.

methodsA population-based sample of 230 JA, 91 AA, and 291 Korean men aged 40-49 was examined for indices of obesity, i.e., visceral and subcutaneous adipose tissue (VAT and SAT, respectively), waist circumference (WC), and body-mass index (BMI), and for lipoprotein subfractions by nuclear-magnetic-resonance spectroscopy. Multiple regression analyses were performed in each of the three ethnic groups to examine the associations of each index of obesity with lipoprotein.

resultsVAT had significant positive associations with total and small low-density lipoprotein (LDL) and a significant negative association with large high-density lipoprotein (HDL) in all three ethnicities (p < 0.01). SAT, WC, and BMI had significant positive associations with total and small LDL in only JA and Koreans, while these indices had significant inverse associations with large HDL in all ethnic groups (p < 0.01). Compared to SAT, VAT had larger

conclusionsVAT is significantly associated with total and small LDL and large HDL in all three ethnic groups. The associations of SAT, WC, and BMI with lipoprotein subfractions are weaker compared to VAT in all three ethnic groups.

Indexed as

body-mass indexlipoprotein subfractionssubcutaneous adipose tissuevisceral adipose tissuewaist circumference

Identifiers

PMID25068101
PMCPMC4110345
OpenAlexW2147535619

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.