Evidence map›Paper›PMID 25068089›Full record

ArticleAdipocyte2014

Regulation of S100B in white adipose tissue by obesity in mice.

Laura B Buckman, Emily K Anderson-Baucum, Alyssa H Hasty, Kate Lj Ellacott

Open access · goldAbstract read
In one paragraph

Article in Adipocyte, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. The Multifaceted S100B Protein: A Role in Obesity and Diabetes?International journal of molecular sciences · 2024
    Review
  5. Article
  6. Amyloid-β Processing in Aged S100B Transgenic Mice Is Sex Dependent.International journal of molecular sciences · 2021
    Article
  7. Review
  8. Green synthesis of silver nanoparticles bySaudi journal of biological sciences · 2020
    Article
  9. Review
  10. Article
  11. S100 proteins in obesity: liaisons dangereuses.Cellular and molecular life sciences : CMLS · 2020
    Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Laura B BuckmanDepartment of Molecular Physiology & Biophysics; Vanderbilt University Medical Center; Nashville, TN USA.
Emily K Anderson-BaucumDepartment of Molecular Physiology & Biophysics; Vanderbilt University Medical Center; Nashville, TN USA.
Alyssa H HastyDepartment of Molecular Physiology & Biophysics; Vanderbilt University Medical Center; Nashville, TN USA.
Kate Lj EllacottDepartment of Molecular Physiology & Biophysics; Vanderbilt University Medical Center; Nashville, TN USA.
Nashville Oncology Associates · USVanderbilt University Medical Center · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
RESEARCH TRAINING PROGRAM IN DIABETES AND OBESITYT32DK064466 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Carmella Evans-Molina, RONALD C WEK · 2003 to 2026
$5.2M
NIDDK NIH HHS P30 DK058404NIDDK NIH HHS T32 DK064466NIDDK NIH HHS U24 DK059637
6 · The paper itself

Abstract

S100B is a calcium binding protein found in adipose tissue; however, relatively little is known about the physiologic regulation or distribution of the protein within this organ. We examined plasma S100B concentration and white adipose tissue (WAT) s100b mRNA levels in lean and diet-induced obese (DIO) mice. Plasma S100B levels were increased by obesity. In WAT, s100b gene expression was also significantly increased by obesity and this increase was reversed following weight-loss. s100b gene expression was detected in both the adipocyte-enriched and stromal-vascular fractions of WAT; however, the increase in s100b gene expression in obese animals was only detected in the adipocyte-enriched fraction. Our results support published in vitro data indicating that WAT S100B may contribute to obesity-associated inflammation.

Indexed as

adipocyteadiposeadiposityreceptor for advanced glycation end-productsS100Bweight loss

Identifiers

PMID25068089
PMCPMC4110099
OpenAlexW1990754061

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.